Covalent organic frameworks for biomedical applications

A Esrafili, A Wagner, S Inamdar… - Advanced Healthcare …, 2021 - Wiley Online Library
Covalent organic frameworks (COFs) are porous organic polymeric materials that are
composed of organic elements and linked together by the thermodynamically stable …

Pemphigus: a comprehensive review on pathogenesis, clinical presentation and novel therapeutic approaches

R Pollmann, T Schmidt, R Eming, M Hertl - Clinical reviews in allergy & …, 2018 - Springer
Pemphigus is a group of rare, potentially devastating autoimmune diseases of the skin and
mucous membranes with high morbidity and potentially lethal outcome. The major clinical …

Gliadin nanoparticles induce immune tolerance to gliadin in mouse models of celiac disease

TL Freitag, JR Podojil, RM Pearson, FJ Fokta, C Sahl… - Gastroenterology, 2020 - Elsevier
Background & Aims Celiac disease could be treated, and potentially cured, by restoring T-
cell tolerance to gliadin. We investigated the safety and efficacy of negatively charged 500 …

Immunologically effective biomaterials

Q Wei, Y Su, H Xin, L Zhang, J Ding… - ACS Applied Materials & …, 2021 - ACS Publications
Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

Nanoparticles for the induction of antigen-specific immunological tolerance

TK Kishimoto, RA Maldonado - Frontiers in immunology, 2018 - frontiersin.org
Antigen-specific immune tolerance has been a long-standing goal for immunotherapy for the
treatment of autoimmune diseases and allergies and for the prevention of allograft rejection …

Nanoparticle‐based nanomedicines to promote cancer immunotherapy: recent advances and future directions

J Liu, R Zhang, ZP Xu - Small, 2019 - Wiley Online Library
Cancer immunotherapy is a promising cancer terminator by directing the patient's own
immune system in the fight against this challenging disorder. Despite the monumental …

Current advances in the development of novel polymeric nanoparticles for the treatment of neurodegenerative diseases

A Cano, E Sanchez-Lopez, M Ettcheto… - …, 2020 - Taylor & Francis
Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …

Two-dimensional layered double hydroxide nanoadjuvant: recent progress and future direction

LX Zhang, J Hu, YB Jia, RT Liu, T Cai, ZP Xu - Nanoscale, 2021 - pubs.rsc.org
Layered double hydroxide (LDH) is a 'sandwich'-like two-dimensional clay material that has
been systematically investigated for biomedical application in the past two decades. LDH is …

Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury

J Park, Y Zhang, E Saito… - Proceedings of the …, 2019 - National Acad Sciences
Traumatic primary spinal cord injury (SCI) results in paralysis below the level of injury and is
associated with infiltration of hematogenous innate immune cells into the injured cord …

Use of polymeric nanoparticle platform targeting the liver to induce treg-mediated antigen-specific immune tolerance in a pulmonary allergen sensitization model

Q Liu, X Wang, X Liu, S Kumar, G Gochman, Y Ji… - ACS …, 2019 - ACS Publications
Nanoparticles (NPs) can be used to accomplish antigen-specific immune tolerance in
allergic and autoimmune disease. The available options for custom-designing tolerogenic …