Metabolic reprogramming in prostate cancer

F Ahmad, MK Cherukuri, PL Choyke - British journal of cancer, 2021 - nature.com
Although low risk localised prostate cancer has an excellent prognosis owing to effective
treatments, such as surgery, radiation, cryosurgery and hormone therapy, metastatic …

[HTML][HTML] Lipid metabolism alteration contributes to and maintains the properties of cancer stem cells

H Li, Z Feng, ML He - Theranostics, 2020 - ncbi.nlm.nih.gov
Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …

A Cholesterol Metabolic Regulated Hydrogen‐Bonded Organic Framework (HOF)‐Based Biotuner for Antibody Non‐Dependent Immunotherapy Tailored for …

N Yin, Y Wang, Y Liu, R Niu, S Zhang, Y Cao… - Advanced …, 2023 - Wiley Online Library
The metabolic reprogramming of glioblastoma (GBM) poses a tremendous obstacle to
effective immunotherapy due to its impact on the immunosuppressive microenvironment. In …

Metabolic drivers of invasion in glioblastoma

JH Garcia, S Jain, MK Aghi - Frontiers in cell and developmental …, 2021 - frontiersin.org
Glioblastoma is a primary malignant brain tumor with a median survival under 2 years. The
poor prognosis glioblastoma caries is largely due to cellular invasion, which enables escape …

Intracavitary Spraying of Nanoregulator‐Encased Hydrogel Modulates Cholesterol Metabolism of Glioma‐Supportive Macrophage for Postoperative Glioblastoma …

Y Dong, J Zhang, Y Wang, Y Zhang… - Advanced …, 2024 - Wiley Online Library
Glioblastoma multiforme (GBM) is notoriously resistant to immunotherapy due to its intricate
immunosuppressive tumor microenvironment (TME). Dysregulated cholesterol metabolism …

Glioblastoma metabolism: insights and therapeutic strategies

C Bernhard, D Reita, S Martin, N Entz-Werle… - International Journal of …, 2023 - mdpi.com
Tumor metabolism is emerging as a potential target for cancer therapies. This new approach
holds particular promise for the treatment of glioblastoma, a highly lethal brain tumor that is …

New insight into brain disease therapy: nanomedicines-crossing blood–brain barrier and extracellular space for drug delivery

Z Gu, H Chen, H Zhao, W Yang, Y Song… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Brain diseases including brain tumor, Alzheimer's disease, Parkinson's disease,
etc. are difficult to treat. The blood–brain barrier (BBB) is a major obstacle for drug delivery …

Cholesterol, oxysterols and LXRs in breast cancer pathophysiology

H Nazih, JM Bard - International journal of molecular sciences, 2020 - mdpi.com
Breast cancer is the most frequent cancer among women. In 2018, it is estimated that
627,000 women died from breast cancer. This is approximately 15% of all cancer deaths …

Drug repurposing for glioblastoma and current advances in drug delivery—a comprehensive review of the literature

S Alomari, I Zhang, A Hernandez, CY Kraft, D Raj… - Biomolecules, 2021 - mdpi.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with an
extremely poor prognosis. There is a dire need to develop effective therapeutics to …

Fatty acids, CD36, thrombospondin-1, and CD47 in glioblastoma: Together and/or separately?

C Tanase, AM Enciu, E Codrici, ID Popescu… - International Journal of …, 2022 - mdpi.com
Glioblastoma (GBM) is one of the most aggressive tumors of the central nervous system,
characterized by a wide range of inter-and intratumor heterogeneity. Accumulation of fatty …