Chinese single herbs and active ingredients for postmenopausal osteoporosis: From preclinical evidence to action mechanism

J Lin, J Zhu, Y Wang, N Zhang, HJ Gober, X Qiu… - Bioscience …, 2017 - jstage.jst.go.jp
Postmenopausal osteoporosis is a systemic metabolic skeletal disease generally ascribable
to a dearth of estrogen. Whether traditional Chinese medicine is effective in management of …

Herb medicines against osteoporosis: active compounds & relevant biological mechanisms

L Wu, Z Ling, X Feng, C Mao… - Current topics in medicinal …, 2017 - ingentaconnect.com
Osteoporosis is one of common bone disorders, affecting millions of people worldwide.
Treatments of osteoporosis consist of pharmacotherapy and non-pharmacological …

[HTML][HTML] Effect of flavonoids from Rhizoma Drynariae on osteoporosis rats and osteocytes

H Jin, N Jiang, W Xu, Z Zhang, Y Yang, J Zhang… - Biomedicine & …, 2022 - Elsevier
In this experimental study, we evaluated the protective effects and the safety of main
flavanones derived from Rhizoma Drynariae (Gusuibu) in vitro and in vivo. The MTT assay …

Separation and detection of minor constituents in herbal medicines using a combination of heart-cutting and comprehensive two-dimensional liquid chromatography

X Qiao, W Song, S Ji, Y Li, Y Wang, R Li, R An… - … of Chromatography A, 2014 - Elsevier
Herbal medicines contain a large number of minor constituents, which could contribute to
their therapeutic effects and provide valuable lead compounds for drug discovery. However …

Gu Sui Bu (Drynaria fortunei J. Sm.) antagonizes glucocorticoid-induced mineralization reduction in zebrafish larvae by modulating the activity of osteoblasts and …

CH Peng, WY Lin, CY Li, KK Dharini, CY Chang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Gu Sui Bu (GSB), the dried rhizome of Drynaria
fortunei J. Sm., is widely used in traditional Chinese medicine for treating fractures and …

[HTML][HTML] Rhizoma drynariae total flavonoids inhibit the inflammatory response and matrix degeneration via MAPK pathway in a rat degenerative cervical intervertebral …

K Zhao, M Chen, T Liu, P Zhang, S Wang, X Liu… - Biomedicine & …, 2021 - Elsevier
Rhizoma drynariae total flavonoids (RDTF) are extracted from Drynaria fortunei J. Sm (D.
fortunei), which was a Chinese herb commonly used to treat fractures and bruises. Modern …

Metabolite profiling of Drynariae Rhizoma using 1H NMR and HPLC coupled with multivariate statistical analysis

Y Dong, K Toume, S Kimijima, H Zhang, S Zhu… - Journal of Natural …, 2023 - Springer
Drynariae Rhizoma has been used to treat bone diseases and kidney deficiency in
traditional medicine. Recently its aqueous extract was reported to enhance memory function …

Characterization of chemical profile and quantification of representative components of DanLou tablet, a traditional Chinese medicine prescription, by UHPLC-Q/TOF …

P Lin, Q Wang, Y Liu, Z Qin, H Gao, M Ye… - … of Pharmaceutical and …, 2020 - Elsevier
DanLou tablet (DLT), a famous traditional Chinese medicine prescription (TCMP) consisting
of 10 herbal medicines, is extensively used for the treatment of angina pectoris and acute …

Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC‐MS/MS after Oral Administration of Drynariae rhizoma Extract

ZL Xu, MY Xu, HT Wang, QX Xu, MY Liu… - Journal of Analytical …, 2018 - Wiley Online Library
As a traditional Chinese medicine, Drynariae rhizoma (Kunze ex Mett.) J. Sm. has been
used to treat osteoporosis and bone resorption for 2500 years. Based on the previous study …

Drynaria fortunei Promoted Angiogenesis Associated With Modified MMP-2/TIMP-2 Balance and Activation of VEGF Ligand/Receptors Expression

ST Huang, CC Chang, JHS Pang, HS Huang… - Frontiers in …, 2018 - frontiersin.org
Background and Purpose: Drynaria fortunei J. Sm (D. fortunei), known as Gu-Sui-Bu, is used
in traditional Chinese medicine to treat common injuries, including bone fractures and …