Current antivirals and novel botanical molecules interfering with herpes simplex virus infection

DM Álvarez, E Castillo, LF Duarte, J Arriagada… - Frontiers in …, 2020 - frontiersin.org
Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent within the
human population and are characterized by lifelong infections and sporadic recurrences …

Polysaccharides and their derivatives as potential antiviral molecules

H Claus-Desbonnet, E Nikly, V Nalbantova… - Viruses, 2022 - mdpi.com
In the current context of the COVID-19 pandemic, it appears that our scientific resources and
the medical community are not sufficiently developed to combat rapid viral spread all over …

Robust antiviral activity of commonly prescribed antidepressants against emerging coronaviruses: in vitro and in silico drug repurposing studies

O Kutkat, Y Moatasim, AA Al‐Karmalawy… - Scientific Reports, 2022 - nature.com
During the current coronavirus disease 2019 (COVID-19) pandemic, symptoms of
depression are commonly documented among both symptomatic and asymptomatic …

Bioactive Azadirachta indica and Melia azedarach leaves extracts with anti-SARS-CoV-2 and antibacterial activities

BA Hemdan, A Mostafa, MM Elbatanony, AM El-Feky… - PLoS …, 2023 - journals.plos.org
The leaves of Azadirachta indica L. and Melia azedarach L., belonging to Meliaceae family,
have been shown to have medicinal benefits and are extensively employed in traditional folk …

Surface‐Anchored Acetylcholine Regulates Band‐Edge States and Suppresses Ion Migration in a 21%‐Efficient Quadruple‐Cation Perovskite Solar Cell

Z Zhang, J Jiang, X Liu, X Wang, L Wang, Y Qiu… - Small, 2022 - Wiley Online Library
Although incorporating multiple halogen (bromine) anions and alkali (rubidium) cations can
improve the open‐circuit voltage (Voc) of perovskite solar cells (PSCs), severe voltage loss …

Robust Antiviral Activity of Santonica Flower Extract (Artemisia cina) against Avian and Human Influenza A Viruses: In Vitro and Chemoinformatic Studies

A Hegazy, I Mostafa, YAMM Elshaier, SH Mahmoud… - ACS …, 2022 - ACS Publications
The evolution of drug-resistant viral strains following natural acquisition of resistance
mutations is a major obstacle to antiviral therapy. Besides the improper prescription of the …

Potential of cytochrome P450, a family of xenobiotic metabolizing enzymes, in cancer therapy

RD Singh, A Avadhesh, G Sharma… - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Targeted cancer therapy with minimal off-target consequences has shown
promise for some cancer types. Although cytochrome P450 (CYP) consists of 18 families …

In Vitro and In Vivo Biological Activities of Dipicolinate Oxovanadium(IV) Complexes

K Choroba, B Filipe, A Świtlicka… - Journal of Medicinal …, 2023 - ACS Publications
The work is focused on anticancer properties of dipicolinate (dipic)-based vanadium (IV)
complexes [VO (dipic)(N∩ N)] bearing different diimines (2-(1 H-imidazol-2-yl) pyridine, 2-(2 …

Glass Microneedles: A Case Study for Regulatory Approval Using a Quality by Design Approach

Z Sartawi, C Blackshields, A Ariamanesh… - Advanced …, 2023 - Wiley Online Library
In this paper, a roadmap is provided for the regulatory approval of one of the exciting and
dynamic drug delivery fields, microneedles, by using a Quality by Design approach to …

Physical and functional characterization of PLGA nanoparticles containing the antimicrobial peptide SAAP-148

M Ali, ME van Gent, AM de Waal… - International Journal of …, 2023 - mdpi.com
Synthetic antimicrobial and antibiofilm peptide (SAAP-148) commits significant antimicrobial
activities against antimicrobial resistant (AMR) planktonic bacteria and biofilms. However …