IL-13 effector functions
TA Wynn - Annual review of immunology, 2003 - annualreviews.org
IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class
II expression, promoted IgE class switching and inhibited inflammatory cytokine production …
II expression, promoted IgE class switching and inhibited inflammatory cytokine production …
Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1
Interleukin (IL)-13 is a key mediator of tissue fibrosis caused by T helper cell type 2
inflammation. We hypothesized that the fibrogenic effects of IL-13 are mediated by …
inflammation. We hypothesized that the fibrogenic effects of IL-13 are mediated by …
Regulation and function of the interleukin 13 receptor α 2 during a T helper cell type 2–dominant immune response
MG Chiaramonte, M Mentink-Kane… - The Journal of …, 2003 - rupress.org
Highly polarized type 2 cytokine responses can be harmful and even lethal to the host if they
are too vigorous or persist too long. Therefore, it is important to elucidate the mechanisms …
are too vigorous or persist too long. Therefore, it is important to elucidate the mechanisms …
Compartmentalized production of CCL17 in vivo: strong inducibility in peripheral dendritic cells contrasts selective absence from the spleen
J Alferink, I Lieberam, W Reindl, A Behrens… - The Journal of …, 2003 - rupress.org
Dendritic cells (DCs) fulfill an important regulatory function at the interface of the innate and
adaptive immune system. The thymus and activation-regulated chemokine (TARC/CCL17) is …
adaptive immune system. The thymus and activation-regulated chemokine (TARC/CCL17) is …
Immunological analogy between allograft rejection, recurrent abortion and pre-eclampsia–the same basic mechanism?
JR Wilczyński - Human immunology, 2006 - Elsevier
There are still controversies concerning the role of immunological mechanisms engaged
both in recurrent abortions (RA) and pre-eclampsia (PE). According to some opinions …
both in recurrent abortions (RA) and pre-eclampsia (PE). According to some opinions …
Development of an antibody specific to major histocompatibility antigens detectable by flow cytometry after lung transplant is associated with bronchiolitis obliterans …
SM Palmer, RD Davis, D Hadjiliadis, MI Hertz… - …, 2002 - journals.lww.com
Background. Chronic allograft rejection manifested as bronchiolitis obliterans syndrome
(BOS) is the leading cause of late death after lung transplantation. Although increasing …
(BOS) is the leading cause of late death after lung transplantation. Although increasing …
Induction of tolerance using Fas ligand: a double-edged immunomodulator
Apoptosis mediated by Fas ligand (FasL) interaction with Fas receptor plays a pivotal
regulatory role in immune homeostasis, immune privilege, and self-tolerance. FasL …
regulatory role in immune homeostasis, immune privilege, and self-tolerance. FasL …
Detection of donor-specific anti-HLA antibodies with flow cytometry in eluates and sera from renal transplant recipients with chronic allograft nephropathy1
L Martin, F Guignier, C Mousson, D Rageot… - …, 2003 - journals.lww.com
Background. Chronic allograft nephropathy (CAN), which remains the main cause of graft
loss after kidney transplantation, is still poorly understood. Because anti-HLA antibodies …
loss after kidney transplantation, is still poorly understood. Because anti-HLA antibodies …
Regulatory functions of self-restricted MHC class II allopeptide-specific Th2 clones in vivo
AM Waaga, M Gasser… - The Journal of …, 2001 - Am Soc Clin Investig
We studied T-cell clones generated from grafts of rejecting and tolerant animals and
investigated the regulatory function of Th2 clones in vitro and in vivo. To prevent allograft …
investigated the regulatory function of Th2 clones in vitro and in vivo. To prevent allograft …