Neonicotinoids have been used to protect crops and animals from insect pests since the
1990s, but there are concerns regarding their adverse effects on nontarget organisms …

Resistance development and limited lepidopteran activities call for the discovery of “super-
neonicotinoids” solving these problems. Compounds with the cis-configuration offer an …

A series of divalent and oxabridged neonicotinoids were synthesized by reactions of
nitromethylene analogues of imidacloprid and dialdehydes, and their structures were …

Imidacloprid is a nicotinic acetylcholine receptor (nAChR) agonist with potent insecticidal
activity. However, resistance to imidacloprid is a significant threat and has been identified in …

BACKGROUND: Cycloxaprid with cis‐configuration is a novel neonicotinoid insecticide,
developed in China, that has good industrialisation prospects for its high activity against …

A novel chemotype insecticide flupyrimin (FLP)[N-[(E)-1-(6-chloro-3-pyridinylmethyl) pyridin-
2 (1 H)-ylidene]-2, 2, 2-trifluoroacetamide], discovered by Meiji Seika Pharma, has unique …

A simple and straightforward addition or defluorination of α-(trifluoromethyl) styrenes with 2-
nitroimino-imidazolidine (2a), 2-(nitromethylene) imidazolidine (2b), 2-cyanoimino …

Abstract BACKGROUND Sulfoxaflor (Isoclast™ active), a new sulfoximine‐class insecticide,
targets sap‐feeding insect pests, including those resistant to neonicotinoids. Sulfoxaflor acts …

This investigation defines the roles of various amino acids, neighboring key conserved
amino acids in loops C and D of the nicotinic acetylcholine (ACh) receptor (nAChR), in the …

Concise and selective: the procedure-controlled synthesis of the title compounds has been
achieved for the first time by an organolithium-promoted convergent tandem annulation …