Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …

Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Oxidative stress is important in the pathophysiology of obesity, altering regulatory factors of
mitochondrial activity, modifying the concentration of inflammation mediators associated with …

Reactive oxygen species (ROS), superoxide anion and hydrogen peroxide, are generated
as byproducts of oxidative phosphorylation in the mitochondria or via cell signaling-induced …

Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

The transcription factor nuclear factor-κB (NF-κB) modulates gene expression in diverse
cellular processes such as innate immune response, embryogenesis and organ …

Remarkable interest has risen in the idea that oxidative/nitrosative stress is mediated in the
etiology of numerous human diseases. Oxidative/Nitrosative stress is the result of an …

Redox biological reactions are now accepted to bear the Janus faceted feature of promoting
both physiological signaling responses and pathophysiological cues. Endogenous …

Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …

The regulatory mechanisms by which hydrogen peroxide (H 2 O 2) modulates the activity of
transcription factors in bacteria (OxyR and PerR), lower eukaryotes (Yap1, Maf1, Hsf1 and …