The “new” head and neck cancer patient—young, nonsmoker, nondrinker, and HPV positive: evaluation

DG Deschler, JD Richmon… - … --Head and Neck …, 2014 - journals.sagepub.com
Objective The near epidemic rise of the incidence of human papillomavirus (HPV)-related
oropharyngeal squamous cell carcinomas (OPSCC) presents the practitioner with a “new” …

Human papillomavirus testing in head and neck carcinomas: guideline from the College of American Pathologists

JS Lewis Jr, B Beadle, JA Bishop… - … of pathology & …, 2018 - meridian.allenpress.com
Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

The role of transoral robotic surgery, transoral laser microsurgery, and lingual tonsillectomy in the identification of head and neck squamous cell carcinoma of …

TS Fu, A Foreman, DP Goldstein… - … -Head & Neck …, 2016 - journals.sagepub.com
Background Squamous cell carcinoma of the head and neck can present as a cervical
metastasis from an unknown primary site. Recently, transoral robotic surgery (TORS) and …

Diagnosis and management of squamous cell carcinoma of unknown primary in the head and neck: ASCO guideline

E Maghami, N Ismaila, A Alvarez… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based recommendations to practicing physicians and other
health care providers on the diagnosis and management of squamous cell carcinoma of …

On-demand intracellular amplification of chemoradiation with cancer-specific plasmonic nanobubbles

EY Lukianova-Hleb, X Ren, RR Sawant, X Wu… - Nature medicine, 2014 - nature.com
Chemoradiation-resistant cancers limit treatment efficacy and safety. We show here the
cancer cell–specific, on-demand intracellular amplification of chemotherapy and …

A new paradigm for the diagnosis and management of unknown primary tumors of the head and neck: a role for transoral robotic surgery

V Mehta, P Johnson, A Tassler, S Kim… - The …, 2013 - Wiley Online Library
Abstract Objectives/Hypothesis: In 2% to 3% of patients with cancer metastatic to cervical
lymph nodes, a primary tumor will not be found despite exhaustive diagnostic efforts. The …

Investigation and management of the unknown primary with metastatic neck disease: United Kingdom National Multidisciplinary Guidelines

K Mackenzie, M Watson, P Jankowska… - The Journal of …, 2016 - cambridge.org
This is the official guideline endorsed by the specialty associations involved in the care of
head and neck cancer patients in the UK. It discusses the evidence base pertaining to the …

p16 status, pathologic and clinical characteristics, biomolecular signature, and long‐term outcomes in head and neck squamous cell carcinomas of unknown primary

LM Keller, TJ Galloway, T Holdbrook, K Ruth… - Head & …, 2014 - Wiley Online Library
Background The purpose of this study was to report associations between p16 status,
clinicopathologic characteristics, and outcomes for head and neck squamous cell carcinoma …

Comprehensive management of HPV‐related squamous cell carcinoma of the head and neck of unknown primary

E Rassy, P Nicolai, N Pavlidis - Head & Neck, 2019 - Wiley Online Library
Background Human papillomavirus (HPV)‐related squamous cell carcinoma of unknown
primary (SCCUP) is currently rising in incidence but lacks a validated management …

[HTML][HTML] Transoral tongue base mucosectomy for the identification of the primary site in the work-up of cancers of unknown origin: systematic review and meta-analysis

S Farooq, S Khandavilli, J Dretzke, D Moore… - Oral oncology, 2019 - Elsevier
Background The use of transoral robotic surgery (TORS) and laser microsurgery (TLM) in
the diagnosis and identification of the site of the unknown primary has become increasingly …