M Wu, Y Zhai, X Liang, W Chen, R Lin, L Ma… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD), the most common cause of dementia, is a complex and multifactorial disease involving genetic and environmental factors, with …
SO Rahman, BP Panda, S Parvez, M Kaundal… - Biomedicine & …, 2019 - Elsevier
With the constant failure of the clinical trials continuous exploration of a therapeutic target against Alzheimer's disease (AD) is the utmost need. Numerous studies have supported the …
S Squillace, ML Niehoff, TM Doyle… - The Journal of …, 2022 - Am Soc Clin Investig
Cancer-related cognitive impairment (CRCI) is a major neurotoxicity affecting more than 50% of cancer survivors. The underpinning mechanisms are mostly unknown, and there are …
Alzheimer's disease (AD) is the most devastating neurodegenerative disorder, accounting over 46 million cases of dementia globally. Evidence supports that Brain Insulin Resistance …
Y Bao, Y Zhu, G He, H Ni, C Liu, L Ma… - Drug Design …, 2019 - Taylor & Francis
Background Dexmedetomidine (Dex) was reported to exhibit anti-inflammatory effect in the nervous system. However, the mechanism by which Dex exhibits anti-inflammation effects …
Millions of people worldwide are currently afflicted with neurologic conditions like a seizure, depression, stress, Alzheimer's disease, Parkinson's disease, and Huntington's disease …
Autism comprises a broad range of neurodevelopmental disorders characterized by social communication deficits and repetitive and stereotyped behaviors. Chemokine receptor …
Memory impairment is a result of multiple factors including amyloid-beta (Aβ) accumulation. Several receptors are mediated for Aβ transport and signaling. Moreover, blood lipids are …
R Paul, A Borah - Scientific reports, 2017 - nature.com
There exists an intricate relationship between hypercholesterolemia (elevated plasma cholesterol) and brain functions. The present study aims to understand the impact of …