Synergistic catalysis, a type of plural catalysis which utilizes at least two different catalysts to
enable a reaction between two separately activated substrates, has unlocked a plethora of …

The chiral oxazoline motif is present in many ligands that have been extensively applied in a
series of important metal-catalyzed enantioselective reactions. This Review aims to provide …

The development of efficient and straightforward methods for obtaining all optically active
isomers of structurally rigid spirocycles from readily available starting materials is of great …

Conspectus The ever-present demand for drugs with better efficacy and fewer side effects
continually motivates scientists to explore the vast chemical space. Traditionally, medicinal …

Bimetallic catalysis represents an alternative paradigm for coupling chemistry that
complements the more traditional single-site catalysis approach. In this perspective, recent …

A stereodivergent Pd/Cu catalyst system has been developed for the unprecedented
dynamic kinetic asymmetric transformation (DyKAT) of racemic unsymmetrical 1, 3 …

From its beginnings in the Sonogashira reaction, synergistic dual transition-metal catalysis
has gained increasing prominence and importance. In the past decade, this strategy has …

Both syn‐and anti‐β‐amino alcohols are common structural motifs in natural products, drug
molecules, chiral ligands and catalysts. However, the currently available methods for …

Detailed in this Communication is the enantioselective synthesis of 1, 1-diarylalkanes, a
structure found in a range of pharmaceutical drug agents and natural products, through the …

Although the chemistry of copper has a long history [1a-d], the relatively recent discovery of
N-heterocyclic carbene (NHC) as transition-metal supporting ligands has permitted novel …