Biological therapy in systemic lupus erythematosus, antiphospholipid syndrome, and Sjögren's syndrome: evidence-and practice-based guidance

A Marinho, J Delgado Alves, J Fortuna, R Faria… - Frontiers in …, 2023 - frontiersin.org
Systemic lupus erythematosus (SLE), antiphospholipid syndrome (APS), and Sjögren's
syndrome (SS) are heterogeneous autoimmune diseases. Severe manifestations and …

Advances in the management of systemic lupus erythematosus

EF Morand, R Fernandez-Ruiz, A Blazer, TB Niewold - bmj, 2023 - bmj.com
Systemic lupus erythematosus (SLE) is a severe multisystem autoimmune disease that can
cause injury in almost every body system. While considered a classic example of …

B cells in systemic lupus erythematosus: Targets of new therapies and surveillance tools

I Parodis, M Gatto, C Sjöwall - Frontiers in Medicine, 2022 - frontiersin.org
B cell hyperactivity is a hallmark of the complex autoimmune disease systemic lupus
erythematosus (SLE), which has justified drug development focusing on B cell altering …

Evolving understanding of autoimmune mechanisms and new therapeutic strategies of autoimmune disorders

Y Song, J Li, Y Wu - Signal Transduction and Targeted Therapy, 2024 - nature.com
Autoimmune disorders are characterized by aberrant T cell and B cell reactivity to the body's
own components, resulting in tissue destruction and organ dysfunction. Autoimmune …

B cell-targeted therapies in systemic lupus erythematosus

L Arbitman, R Furie, H Vashistha - Journal of Autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology
that primarily affects women of childbearing age. There is no disease more heterogeneous …

Targeting DORIS remission and LLDAS in SLE: a review

AR Parra Sánchez, RF van Vollenhoven… - Rheumatology and …, 2023 - Springer
Remission is the established therapeutic goal for patients with systemic lupus
erythematosus (SLE) and is currently defined by the widely adopted Definition Of Remission …

Belimumab for systemic lupus erythematosus–Focus on lupus nephritis

M Plüß, S Piantoni, B Tampe, AHJ Kim… - Human Vaccines & …, 2022 - Taylor & Francis
In recent years, advances in the treatment and management of patients with systemic lupus
erythematosus (SLE) have improved their life expectancy and quality of life. However, lupus …

[HTML][HTML] Системная красная волчанка: история и современность

ЕЛ Насонов, СК Соловьев… - Научно-практическая …, 2022 - cyberleninka.ru
Системная красная волчанка (СКВ)-системное аутоиммунное ревматическое
заболевание неизвестной этиологии, характеризующееся гиперпродукцией …

Translational implications of newly characterized pathogenic pathways in systemic lupus erythematosus

M Gatto, R Depascale, AL Stefanski… - Best Practice & …, 2023 - Elsevier
Improved characterization of relevant pathogenic pathways in systemic lupus erythematosus
(SLE) has been further delineated over the last decades. This led to the development of …

Dual B-cell targeting therapy ameliorates autoimmune cholangitis

W Zhang, T Shao, PSC Leung, K Tsuneyama… - Journal of …, 2022 - Elsevier
Objective The ability to regulate B cell development has long been recognized to have
therapeutic potential in a variety of autoimmune diseases. However, despite the presence of …