Determination of fungicidal activities against yeasts and molds: lessons learned from bactericidal testing and the need for standardization

MA Pfaller, DJ Sheehan, JH Rex - Clinical microbiology reviews, 2004 - Am Soc Microbiol
In certain unique clinical settings, the ability of the antimicrobial agent administered to kill the
pathogen outright may be quite important. These situations invariably involve infection of a …

Review of newer antifungal and immunomodulatory strategies for invasive aspergillosis

WJ Steinbach, DA Stevens - Clinical Infectious Diseases, 2003 - academic.oup.com
The incidence of invasive aspergillosis is markedly increasing, and mortality remains dismal.
Previously there were only 2 antifungals with activity against Aspergillus, but over the last …

Aspergillus terreus and the Interplay with Amphotericin B: from Resistance to Tolerance?

R Vahedi-Shahandashti, AM Dietl… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Aspergillus terreus is an opportunistic causative agent of invasive aspergillosis and, in most
cases, it is refractory to amphotericin B (AMB) therapy. Notably, AMB-susceptible Aspergillus …

The composition of the culture medium influences the β-1, 3-glucan metabolism of Aspergillus fumigatus and the antifungal activity of inhibitors of β-1, 3-glucan …

C Clavaud, A Beauvais, L Barbin… - Antimicrobial agents …, 2012 - Am Soc Microbiol
In vitro testing of Aspergillus fumigatus susceptibility to echinocandins has always been a
challenge. Using a simple and quick colorimetric method to analyze the activity of inhibitors …

Drug-dependent growth curve reshaping reveals mechanisms of antifungal resistance in Saccharomyces cerevisiae

L Guinn, E Lo, G Balázsi - Communications Biology, 2022 - nature.com
Microbial drug resistance is an emerging global challenge. Current drug resistance assays
tend to be simplistic, ignoring complexities of resistance manifestations and mechanisms …

Aspergillus fumigatus acetate utilization impacts virulence traits and pathogenicity

LNA Ries, P Alves de Castro, L Pereira Silva, C Valero… - MBio, 2021 - Am Soc Microbiol
Aspergillus fumigatus is a major opportunistic fungal pathogen of immunocompromised and
immunocompetent hosts. To successfully establish an infection, A. fumigatus needs to use …

Susceptibility testing of sequential isolates of Aspergillus fumigatus recovered from treated patients

E Dannaoui, J Meletiadis… - Journal of medical …, 2004 - microbiologyresearch.org
Two-hundred sequential Aspergillus fumigatus isolates recovered from 26
immunocompromised patients with invasive aspergillosis or bronchial colonization were …

Aspergillosis

WJ Steinbach, J Loeffler… - Fungal Infections in the …, 2005 - taylorfrancis.com
Aspergillosis refers to infection with any of the> 150 recognized species of the genus
Aspergillus. These are in mould form in the environment, on artificial media, and when …

Fungal prophylaxis following reduced-intensity stem cell transplantation (RIST)

M Kami, O Imataki, S Taniguchi… - … Ishinkin Gakkai Zasshi, 2004 - jstage.jst.go.jp
抄録 造血幹細胞移植は, 進行期造血器腫瘍に対する根治療法として有効性が確立している.
前処置強度を弱めた移植法が開発され, ミニ移植と称されている. ミニ移植では前処置による副作用 …

I. ETIOLOGY AND EPIDEMIOLOGY

WJ Steinbach, J Loeffler, DA Stevens - api.taylorfrancis.com
Aspergilli are ubiquitous in the environment and are associated with decaying matter with
growth in temperatures of 40–50 C, eg, self-heating organic compost. They have been easily …