Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

There is evidence that excessive stress exposure of the brain, mediated through the
neurotoxic effects of cortisol and possibly neuroinflammation, causes damage to brain …

Following the discovery of glucocorticoid receptors in the hippocampus and other brain
regions, research has focused on understanding the effects of glucocorticoids in the brain …

Objective: To investigate any correlation between BMI and brain gray matter volume, we
analyzed 1,428 healthy Japanese subjects by applying volumetric analysis and voxel …

Objective: To investigate the longitudinal relationship between body mass index (BMI), a
major vascular risk factor, and cerebral atrophy, a marker of neurodegeneration, in a …

Although mood disorders have traditionally been regarded as good prognosis diseases, a
growing body of data suggests that the long-term outcome for many patients is often much …

Endogenous Cushing's syndrome (CS), a rare endocrine disorder characterized by cortisol
hypersecretion, is associated with psychiatric and neurocognitive disorders. Major …

Background: Although obesity is associated with structural changes in brain grey matter,
findings have been inconsistent and the precise nature of these changes is unclear …

Background Cushing's syndrome (CS) is characterized by excessive exposure to cortisol,
and is associated with both metabolic and behavioral abnormalities. Symptoms improve …