Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19
C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …
Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction
An integrative multi-modal metabolic phenotyping model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
Rapid and Self-Administrable Capillary Blood Microsampling Demonstrates Statistical Equivalence with Standard Venous Collections in NMR-Based Lipoprotein …
We investigated plasma and serum blood derivatives from capillary blood microsamples
(500 μL, MiniCollect tubes) and corresponding venous blood (10 mL vacutainers). Samples …
(500 μL, MiniCollect tubes) and corresponding venous blood (10 mL vacutainers). Samples …
[HTML][HTML] Quantitative serum NMR spectroscopy stratifies COVID-19 patients and sheds light on interfaces of host metabolism and the immune response with cytokines …
T Rössler, G Berezhnoy, Y Singh, C Cannet… - Metabolites, 2022 - mdpi.com
The complex manifestations of COVID-19 are still not fully decoded on the molecular level.
We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum …
We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum …
Direct low field J-edited diffusional proton NMR spectroscopic measurement of COVID-19 inflammatory biomarkers in human serum
P Nitschke, S Lodge, D Hall, H Schaefer, M Spraul… - Analyst, 2022 - pubs.rsc.org
A JEDI NMR pulse experiment incorporating relaxational, diffusional and J-modulation peak
editing has been implemented for a low field (80 MHz proton resonance frequency) …
editing has been implemented for a low field (80 MHz proton resonance frequency) …
Can NMR-HetCA be a Reliable Prediction Tool for the Direct Identification of Bioactive Substances in Complex Mixtures?
V Amountzias, A Cheilari, A Vontzalidou… - Analytical …, 2024 - ACS Publications
Conventional isolation methods in natural products chemistry are time-consuming and costly
and often result in the isolation of moderately active compounds or the detection of already …
and often result in the isolation of moderately active compounds or the detection of already …
HDL-related parameters and COVID-19 mortality: the importance of HDL function
JT Stadler, H Habisch, F Prüller, H Mangge… - Antioxidants, 2023 - mdpi.com
COVID-19, caused by the SARS-CoV-2 coronavirus, emerged as a global pandemic in late
2019, resulting in significant global public health challenges. The emerging evidence …
2019, resulting in significant global public health challenges. The emerging evidence …
Lysophosphatidylcholine: Potential target for the treatment of chronic pain
J Ren, J Lin, L Yu, M Yan - International Journal of Molecular Sciences, 2022 - mdpi.com
The bioactive lipid lysophosphatidylcholine (LPC), a major phospholipid component of
oxidized low-density lipoprotein (Ox-LDL), originates from the cleavage of …
oxidized low-density lipoprotein (Ox-LDL), originates from the cleavage of …
Urinary phenotyping of SARS-CoV-2 infection connects clinical diagnostics with metabolomics and uncovers impaired NAD+ pathway and SIRT1 activation
Objectives The stratification of individuals suffering from acute and post-acute SARS-CoV-2
infection remains a critical challenge. Notably, biomarkers able to specifically monitor viral …
infection remains a critical challenge. Notably, biomarkers able to specifically monitor viral …
Stratification of Sepsis Patients on Admission into the Intensive Care Unit According to Differential Plasma Metabolic Phenotypes
Delayed diagnosis of patients with sepsis or septic shock is associated with increased
mortality and morbidity. UPLC-MS and NMR spectroscopy were used to measure panels of …
mortality and morbidity. UPLC-MS and NMR spectroscopy were used to measure panels of …