Cell size and cell count are adaptively regulated and intimately linked to growth and
function. Yet, despite their widespread relevance, the relation between cell size and count …

Size and shape are important aspects of nuclear structure. While normal cells maintain
nuclear size within a defined range, altered nuclear size and shape are associated with a …

The nucleus displays a wide range of sizes and shapes in different species and cell types,
yet its size scaling and many of the key structural constituents that determine its shape are …

The invariant development and transparent body of the nematode Caenorhabditis elegans
enables complete delineation of cell lineages throughout development. Despite extensive …

Intercellular communications are essential for cell proliferation and differentiation during
plant embryogenesis. However, analysis of intercellular communications in living material in …

INTRODUCTION Within each animal species, embryonic development is highly
reproducible, ensuring the faithful production of a complex organism with precisely arranged …

The spindle assembly checkpoint (SAC) delays mitotic progression when chromosomes are
not properly attached to microtubules of the mitotic spindle. Cells vary widely in the extent to …

Eukaryote cell division features a chromosome compaction–decompaction cycle that is
synchronized with their physical and topological segregation. It has been proposed that …

High throughput experimental approaches are increasingly allowing for the quantitative
description of cellular and organismal phenotypes. Distilling these large volumes of complex …

Morphogenesis is a precise and robust dynamic process during metazoan embryogenesis,
consisting of both cell proliferation and cell migration. Despite the fact that much is known …