The 677 C/T MTHFR polymorphism is associated with essential hypertension, coronary artery disease, and higher homocysteine levels
BACKGROUND: Essential hypertension (EH) and cardiovascular disease are common,
multifactorial disorders likely to be influenced by multiple genes of modest effect. The C677T …
multifactorial disorders likely to be influenced by multiple genes of modest effect. The C677T …
Genetic polymorphisms involved in folate metabolism and concentrations of methylmalonic acid and folate on plasma homocysteine and risk of coronary artery …
PM Biselli, AR Guerzoni, MF de Godoy… - Journal of thrombosis …, 2010 - Springer
Objectives Alterations in the enzymes involved in homocysteine (Hcy) metabolism or vitamin
deficiency could play a role in coronary artery disease (CAD) development. This study …
deficiency could play a role in coronary artery disease (CAD) development. This study …
Association between homocysteine and coronary artery disease—trend over time and across the regions: a systematic review and meta-analysis
Background The association of homocysteine with coronary artery disease (CAD) has been
explored previously with mixed findings. The present Systematic Review and Meta-Analysis …
explored previously with mixed findings. The present Systematic Review and Meta-Analysis …
Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease
M Agirbasli, AI Guney, HS Ozturhan… - European Journal of …, 2011 - academic.oup.com
Background Association studies in the Turkish population have investigated the single locus
effects of different gene polymorphisms on coronary artery disease (CAD). CAD is a complex …
effects of different gene polymorphisms on coronary artery disease (CAD). CAD is a complex …
Role of MTHFR C677T polymorphism in ischemic stroke
I Panigrahi, T Chatterjee, A Biswas, M Behari… - Neurology …, 2006 - journals.lww.com
Background: Homozygosity for MTHFR C677T polymorphism can lead to significantly high
homocysteine levels and hyperhomocysteinemia is an important risk factor for thrombotic …
homocysteine levels and hyperhomocysteinemia is an important risk factor for thrombotic …
[PDF][PDF] Genetic factors of the hemostatic system in young patients with myocardial infarction
I Isordia-Salas, AL Mendoza-Valdez… - Cir Cir, 2010 - researchgate.net
Background: Coronary artery disease (CAD) is the first cause of death worldwide and
represents a public health issue in our country. Acute myocardial infarction (AMI) represents …
represents a public health issue in our country. Acute myocardial infarction (AMI) represents …
Hyperhomocysteinemia prevalence among patients with venous thromboembolism
The aim of this study is to evaluate the plasma total homocysteine level in patients with
venous thromboembolism (VTE) and to investigate the effect of different risk factors on …
venous thromboembolism (VTE) and to investigate the effect of different risk factors on …
C677T polymorphism of the 5, 10 MTHFR gene in young Mexican subjects with ST-elevation myocardial infarction
I Isordia-Salas, A Trejo-Aguilar… - Archives of medical …, 2010 - Elsevier
BACKGROUND AND AIMS: The C677T polymorphism of 5, 10 methylenetetrahydrofolate
reductase (MTHFR) gene has been associated with hypertension and coronary artery …
reductase (MTHFR) gene has been associated with hypertension and coronary artery …
Homocysteine and methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Tunisian patients with severe coronary artery disease
L Ghazouani, N Abboud, N Mtiraoui, W Zammiti… - Journal of thrombosis …, 2009 - Springer
Elevation in homocysteine and methylenetetrahydrofolate reductase (MTHFR) gene
variants, C677T and A1298C, have been linked with atherothrombosis. However their exact …
variants, C677T and A1298C, have been linked with atherothrombosis. However their exact …
Association between polymorphism of MTHFR c.677C>T and risk of cardiovascular disease in Turkish population: a meta-analysis for 2.780 cases and 3.022 controls
V Bozok Çetintaş, C Gündüz - Molecular biology reports, 2014 - Springer
Cardiovascular diseases (CVDs) remain the main cause of morbidity and mortality around
the world. A common polymorphism c. 677C> T has been identified in the gene coding for …
the world. A common polymorphism c. 677C> T has been identified in the gene coding for …