Primary cilia project in a single copy from the surface of most vertebrate cell types; they
detect and transmit extracellular cues to regulate diverse cellular processes during …

Intraflagellar transport (IFT) is a form of motor‐dependent cargo transport that is essential for
the assembly, maintenance, and length control of cilia, which play critical roles in motility …

The centrosome was discovered in the late 19th century when mitosis was first described.
Long recognized as a key organelle of the spindle pole, its core component, the centriole …

Primary cilia are microtubule-based organelles that extend from the apical surface of most
mammalian cells, forming when the basal body (derived from the mother centriole) docks at …

Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

Primary cilia protrude from most vertebrate cell bodies and act as specialized 'signalling
antennae'that can substantially lengthen or retract in minutes to hours in response to specific …

Stem cell niches provide resident stem cells with signals that specify their identity. Niche
signals act over a short range such that only stem cells but not their differentiating progeny …

Abstract The mir-34/449 family consists of six homologous miRNAs at three genomic loci.
Redundancy of miR-34/449 miRNAs and their dominant expression in multiciliated epithelia …

The primary cilium is a central signaling hub in cell proliferation and differentiation and is
built and disassembled every cell cycle in many animal cells. Disassembly is critically …

The primary cilium projects from the surface of most vertebrate cells, where it senses
extracellular signals to regulate diverse cellular processes during tissue development and …