Radiotherapy is used in the treatment of approximately 50% of all malignancies including
gastrointestinal cancers. Radiation can be given prior to surgery (neoadjuvant radiotherapy) …

Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …

Radiotherapy is a regimen that uses ionising radiation (IR) to treat cancer. Despite the
availability of several therapeutic options, cancer remains difficult to treat and only a minor …

Radiotherapy (RT) has been viewed as one of the most effective and extensively applied
curatives in clinical cancer therapy. However, the radioresistance of tumor severely …

Simple Summary Cancer cells display among its hallmark genomic instability. This is a
progressive tendency in accumulate genome alteration which contributes to the damage of …

Resistance to neoadjuvant chemoradiation therapy is a significant clinical challenge in the
management of rectal cancer. There is an unmet need to identify the underlying …

Oesophageal adenocarcinoma (OAC) is a disease with an incredibly poor survival rate and
a complex makeup. The growth and spread of OAC tumours are profoundly influenced by …

To meet the anabolic demands of the proliferative potential of tumor cells, malignant cells
tend to rewire their metabolic pathways. Although different types of malignant cells share this …

Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The
current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant …

Abstract Background/Objectives: Only 20–30% of oesophageal adenocarcinoma (OAC)
patients achieve a complete response to neoadjuvant chemo-radiotherapy for locally …