Univocal identification of retinal ganglion cells (RGCs) is an essential prerequisite for
studying their degeneration and neuroprotection. Before the advent of phenotypic markers …

Retinal ganglion cells (RGCs) are the only afferent neurons that can transmit visual
information to the brain. The death of RGCs occurs in the early stages of glaucoma, diabetic …

Autophagy is a conserved feature of lysosome-mediated intracellular degradation.
Dysregulated autophagy is implicated as a contributor in neurodegenerative diseases; …

Clinical and experimental evidence supports that chronic oxidative stress is a primary
contributing factor to numerous retinal degenerative diseases, such as age-related macular …

Background Retinitis pigmentosa is a heterogeneous group of inherited neurodegenerative
retinal disorders characterized by a progressive peripheral vision loss and night vision …

Retinal neurodegenerative diseases involve a scenario of inflammation and cell death that
leads to morphological alterations and visual impairment. Non-ocular inflammatory …

The ubiquitin–proteasome system (UPS) is the main intracellular pathway for modulated
protein turnover, playing an important role in the maintenance of cellular homeostasis. It also …

PURPOSE: The article aims to review foveal involvement in Parkinson's disease. SCOPE:
Clinical observations as well as electrophysiological and anatomical studies in animal …

To quantify the thickness of the inner retinal layers in the foveal pit where the nerve fiber
layer (NFL) is absent, and quantify changes in the ganglion cells and inner plexiform layer …

Ubiquitin C‑terminal hydrolase‑L1 (UCH‑L1), a member of the lesser‑known
deubiquitinating enzyme family, has deubiquitinase and ubiquitin (Ub) ligase activity and the …