Pharmacology of anabolic steroids

AT Kicman - British journal of pharmacology, 2008 - Wiley Online Library
Athletes and bodybuilders have recognized for several decades that the use of anabolic
steroids can promote muscle growth and strength but it is only relatively recently that these …

Androgen misuse and abuse

DJ Handelsman - Endocrine Reviews, 2021 - academic.oup.com
Androgens are potent drugs requiring prescription for valid medical indications but are
misused for invalid, unproven, or off-label reasons as well as being abused without …

[图书][B] Karch's pathology of drug abuse

SB Karch, O Drummer - 2008 - taylorfrancis.com
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative
information focused on the investigation of drug-related deaths and practical approaches to …

Comparison of crystal structures of human androgen receptor ligand‐binding domain complexed with various agonists reveals molecular determinants responsible for …

K Pereira de Jésus‐Tran, PL Côté, L Cantin… - Protein …, 2006 - Wiley Online Library
Androgens exert their effects by binding to the highly specific androgen receptor (AR). In
addition to natural potent androgens, AR binds a variety of synthetic agonist or antagonist …

Advances in male contraception

ST Page, JK Amory, WJ Bremner - Endocrine reviews, 2008 - academic.oup.com
Despite significant advances in contraceptive options for women over the last 50 yr, world
population continues to grow rapidly. Scientists and activists alike point to the devastating …

In vitro profiling of the endocrine disrupting potency of organochlorine pesticides

J Li, N Li, M Ma, JP Giesy, Z Wang - Toxicology letters, 2008 - Elsevier
Some organochlorine pesticides (OCPs) are suspected of modulating the endocrine
systems of humans. Aspects of neuro-endocrine system modulation include interactions …

Metabolism and excretion of anabolic steroids in doping control—new steroids and new insights

P Van Eenoo, FT Delbeke - The Journal of steroid biochemistry and …, 2006 - Elsevier
The use of anabolic steroids in sports is prohibited by the World Anti-Doping Agency. Until
the 1990s, anabolic steroids were solely manufactured by pharmaceutical companies, albeit …

[HTML][HTML] Androgen physiology, pharmacology, use and misuse

DJ Handelsman - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Testosterone, together with its bioactive metabolites dihydrotestosterone and estradiol,
determines the development and maintenance of male sexual differentiation and the …

In silico evaluation of the binding energies of androgen receptor agonists in wild-type and mutational models

ACC Albuquerque, KS Bezerra… - The Journal of …, 2023 - ACS Publications
Anabolic androgenic steroids (AAS) are substances with androgenic and anabolic
characteristics. Among the many side effects of hormone therapy with AAS, the following …

Anabolic steroid abuse: physiological and anaesthetic considerations

PCA Kam, M Yarrow - Anaesthesia, 2005 - Wiley Online Library
This review summarises the physiological and pharmacological effects of the anabolic
steroids used to enhance performance in sports. The anabolic steroids promote muscle …