Ion channels represent the molecular entities that give rise to the cardiac action potential,
the fundamental cellular electrical event in the heart. The concerted function of these …

Cyclic nucleotide-binding domain (CNBD) channels are a family of ion channels in the
voltage-gated K+ channel superfamily that play crucial roles in many physiological …

The deuteron is the simplest compound nucleus, composed of one proton and one neutron.
Deuteron properties such as the root-mean-square charge radius rd and the polarizability …

Voltage-gated potassium (Kv) channels are gated by the movement of the transmembrane
voltage sensor, which is coupled, through the helical S4-S5 linker, to the potassium pore …

Cholinergic neurons in the medial septum (MS) constitute a major source of cholinergic
input to the forebrain and modulate diverse functions, including sensory processing …

The voltage-gated potassium channel AKT1 is responsible for primary K+ uptake in
Arabidopsis roots. AKT1 is functionally activated through phosphorylation and negatively …

It has been suggested that deficient protein trafficking to the cell membrane is the dominant
mechanism associated with type 2 Long QT syndrome (LQT2) caused by Kv11. 1 potassium …

In rod photoreceptors of the retina, the cyclic nucleotide-gated (CNG) channel is composed
of three CNGA and one CNGB subunits, and it closes in response to light activation to …

Voltage-gated sodium channels (Nav) underlie the rapid upstroke of action potentials in
excitable tissues. Binding of channel-interactive proteins is essential for controlling fast and …

The human ether-a-go-go-related gene (hERG) K+ channel is of great medical and
pharmaceutical relevance. Inherited mutations in hERG result in congenital long-QT …