Peptide natural products are important lead structures for human drugs and many
nonribosomal peptides possess antibiotic activity. This makes them interesting targets for …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) have received
much attention in recent years because of their promising bioactivities and the portability of …

Natural bioactive peptide discovery is a challenging and time-consuming process. However,
advances in synthetic biology are providing promising new avenues in peptide engineering …

The S‐glycosyltransferase LmbT, involved in the biosynthesis of lincomycin A, is the only
known enzyme that catalyzes the enzymatic incorporation of rare amino acid L …

Pesticide pollution remains a significant environmental challenge, necessitating the
exploration of sustainable alternatives. Biosurfactants are a class of unconventional surface …

Naturally occurring (native) sugars and carbohydrates contain numerous hydroxyl groups of
similar reactivity,. Chemists, therefore, rely typically on laborious, multi-step protecting-group …

In the course of studies on the enhancement of 1, 2-dibromoethane-induced DNA base pair
mutations by O 6-alkylguanine-DNA alkyltransferase (AGT, MGMT), we discovered the facile …

Glycosylated bacteriocins, known as glycocins, were first discovered in 2011. These
bioactive peptides are produced by bacteria to gain survival advantages. They exhibit …

Glycosyltransferases play a fundamental role in the biosynthesis of glycoproteins and
glycotherapeutics. In this study, we investigated protein glycosyltransferase FlgGT1 …

Mutations that cause loss of function of GlcNAc-1-phosphotransferase (PTase) lead to the
lysosomal storage disorder mucolipidosis II. PTase is the key enzyme of the mannose 6 …