Melatonin in cancer treatment: current knowledge and future opportunities

WH Talib, AR Alsayed, A Abuawad, S Daoud… - Molecules, 2021 - mdpi.com
Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …

[HTML][HTML] Melatonin for the prevention and treatment of cancer

Y Li, S Li, Y Zhou, X Meng, JJ Zhang, DP Xu, HB Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
The epidemiological studies have indicated a possible oncostatic property of melatonin on
different types of tumors. Besides, experimental studies have documented that melatonin …

[HTML][HTML] Cancer-related fatigue: ESMO Clinical Practice Guidelines for diagnosis and treatment

A Fabi, R Bhargava, S Fatigoni, M Guglielmo… - Annals of …, 2020 - Elsevier
Fatigue is the most common symptom experienced by patients during the cancer trajectory
from diagnosis to the end of life and is defined as a distressing, persistent, subjective sense …

[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements

DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | Is Melatonin the “Next Vitamin D”?: A Review of
Emerging Science, Clinical Uses, Safety, and Dietary Supplements Next Article in Journal …

Chemotherapy in patients with early breast cancer: clinical overview and management of long-term side effects

P Di Nardo, C Lisanti, M Garutti, S Buriolla… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Neo/adjuvant therapy for early-stage breast cancer has become increasingly
common in the last few decades; as a consequence, the number of breast cancer survivors …

Melatonin: facts, extrapolations and clinical trials

JA Boutin, DJ Kennaway, R Jockers - Biomolecules, 2023 - mdpi.com
Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

Clinical impact of melatonin on breast cancer patients undergoing chemotherapy; effects on cognition, sleep and depressive symptoms: a randomized, double-blind …

ACS Palmer, M Zortea, A Souza, V Santos, JV Biazús… - PloS one, 2020 - journals.plos.org
This randomized, double-blinded, placebo-controlled trial tested the hypothesis that 20mg of
melatonin before and during the first cycle of adjuvant chemotherapy for breast cancer …

Mechanisms underlying tumor suppressive properties of melatonin

SC Bondy, A Campbell - International journal of molecular sciences, 2018 - mdpi.com
There is considerable evidence that melatonin may be of use in the prevention and
treatment of cancer. This manuscript will review some of the human, animal and cellular …

Promising antineoplastic actions of melatonin

G Favero, E Moretti, F Bonomini, RJ Reiter… - Frontiers in …, 2018 - frontiersin.org
Melatonin is an endogenous indoleamine with an incredible variety of properties and
activities. In recent years, an increasing number of studies have investigated this …

A randomized, controlled, parallel-group, trial on the effects of melatonin on fatigue associated with breast cancer and its adjuvant treatments

A Sedighi Pashaki, K Mohammadian… - Integrative Cancer …, 2021 - journals.sagepub.com
Objective: Fatigue associated with malignant conditions and their treatments is a disabling
condition. This trial assessed the anti-fatigue effects of melatonin coadministration during …