This guideline presents recommendations for the management of patients with hereditary
gastrointestinal cancer syndromes. The initial assessment is the collection of a family history …

Colorectal cancer (CRC) is a multifactorial disease resulting from lifestyle, genetic, and
environmental factors. There are hereditary and non-hereditary CRC types; however, the …

This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

This is a focused update highlighting the most current NCCN Guidelines for diagnosis and
management of Lynch syndrome. Lynch syndrome is the most common cause of hereditary …

Colorectal cancer (CRC) is a complex disease that develops as a consequence of both
genetic and environmental risk factors. A small proportion (3–5%) of cases arise from …

Approximately 35% of patients with colorectal cancer (CRC) have a family history of the
disease attributed to genetic factors, common exposures, or both. Some families with a …

Colorectal cancer is a worldwide problem having global increases in the number of cases
and deaths because of the expanding and aging of the population in both developing and …

Colorectal cancer is one of the most common tumors, and genetic predisposition is one of
the key risk factors in the development of this malignancy. Lynch syndrome and familial …

Abstract Approximately 5–10% of breast cancers may be inheritable, up to 90% of which are
due to mutations in BRCA1 and BRCA2. A substantial minority are caused by non‐BRCA …

Hamartomatous polyposis syndromes are a diverse group of inherited conditions grouped
together because they exhibit hamartomatous rather than epithelial polyp histology. Each …