Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Metastasis remains a pivotal characteristic of cancer and is the primary contributor to cancer-
associated mortality. Despite its significance, the mechanisms governing metastasis are not …

Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the
bloodstream are associated with a poor prognosis, elevated metastatic potential, higher …

Hepatocellular carcinoma (HCC) is a malignant tumor, frequently causing both intrahepatic
and extrahepatic metastases. The overall prognosis of patients with metastatic HCC is poor …

Patients with idiopathic pulmonary fibrosis (IPF) have a high risk of developing lung cancer
compared with the general population. The morbidity of lung cancer in IPF patient ranges …

Distant metastasis mainly occurs through hematogenous dissemination, where suspended
circulating tumor cells (CTCs) experience a considerable level of fluid shear stress. We …

Cancer cells must survive aberrant fluid shear stress (FSS) in the circulation to metastasize.
Herein, we investigate the role that FSS has on colorectal cancer cell apoptosis …

To seed lethal secondary lesions, circulating tumor cells (CTCs) must survive all rate-limiting
factors during hematogenous dissemination, including fluid shear stress (FSS) that poses a …

Glioblastoma multiforme (GBM) is the most severe form of brain cancer in adults,
characterized by its complex vascular network that contributes to resistance to conventional …

When circulating tumor cells (CTCs) travel in circulation, they can be killed by detachment‐
induced anoikis and fluidic shear stress (SS)‐mediated apoptosis. Circulatory treatment …