Typical omega 3 polyunsaturated fatty acids (n-3 PUFAs) are docosahexaenoic acid and
eicosapentaenoic acid in the form of fish oils and α linolenic acid from flaxseed oil …

▪ Abstract Apart from being an important macronutrient, dietary fat has recently gained much
prominence for its role in regulating gene expression. Polyunsaturated fatty acids (PUFAs) …

Stearoyl-CoA Desaturase 1 (SCD1) is the rate limiting enzyme catalyzing the biosynthesis of
monounsaturated fatty acids preferentially from palmitoyl-CoA and stearoyl-CoA forming …

Polyunsaturated fatty acids (PUFAs), specifically the n-3 series, have been implicated in the
prevention of various human diseases, including obesity, diabetes, coronary heart disease …

Abstract The roles of Omega-3 FAs are inflammation antagonists, while Omega-6 FAs are
precursors for inflammation. The plant form of Omega-3 FAs is the short-chain α-linolenic …

The ATP-binding cassette transporters, ABCA1 and ABCG1, are major players in mediating
cellular efflux of phospholipids and cholesterol to apoA-I containing lipoproteins including …

Linoleic and α-linolenic acids are the fatty acids designated as “essential” since they are not
synthesized by mammalian cells and must be provided in the diet. The recent dietary shift …

The liver appears to use the highly unsaturated fatty acid status as a nutrient sensor to
determine whether fatty acids are to be stored or oxidized. In this way highly unsaturated …

The rate-limiting step in 20: 4 (n-6) and 22: 6 (n-3) synthesis is the desaturation of 18: 2 (n-6)
and 18: 3 (n-3) by Δ-6 desaturase. In this report, we demonstrate that n-6 and n-3 PUFAs …

Despite its potential importance in obesity and related disorders, little is known about
regulation of lipogenesis in human adipose tissue. To investigate this area at the molecular …