Amides are unquestionably one of the most important functional groups in organic chemistry because of their presence in numerous interesting molecules such as peptides …
Nucleophilic substitution reactions of alcohols are among the most fundamental and strategically important transformations in organic chemistry. For over half a century, these …
The amide functional group is commonly found in peptides, proteins, pharmaceutical compounds, natural products, and polymers. The synthesis of amides is typically performed …
JE Dander, EL Baker, NK Garg - Chemical science, 2017 - pubs.rsc.org
Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of …
G Meng, P Lei, M Szostak - Organic letters, 2017 - ACS Publications
The first general method is reported for transamidation of secondary carboxamides catalyzed by Pd-NHC (NHC= N-heterocyclic carbene) complexes. Commercially available …
BN Bhawal, B Morandi - Angewandte Chemie International …, 2019 - Wiley Online Library
Transfer hydrogenation, alkene metathesis, and alkyne metathesis possess great value to the synthetic chemistry community. One of the key features of these processes is their …
T Ghosh, S Jana, J Dash - Organic letters, 2019 - ACS Publications
This work discloses transamidation of primary and tertiary amides with a range of aryl, heteroaryl, and aliphatic amines using potassium tert-butoxide. The reaction proceeds at …
P Acosta-Guzmán, A Mateus-Gómez… - Molecules, 2018 - mdpi.com
Amides are undeniably some of the most important compounds in Nature and the chemical industry, being present in biomolecules, materials, pharmaceuticals and many other …
A highly improved and green methodology for the direct amidation of carboxylic acids with amines using silica gel as a solid support and catalyst is described. The scope of this …