The key element of dopamine (DA) neurotransmission is undoubtedly DA transporter (DAT),
a transmembrane protein responsible for the synaptic reuptake of the mediator. Changes in …

Dopamine (DA) signaling via G protein‐coupled receptors is a multifunctional
neurotransmitter and neuroendocrine–immune modulator. The DA nigrostriatal pathway …

Silencing of dopamine transporter (DAT), a main controlling factor of dopaminergic
signaling, results in biochemical and behavioral features characteristic for neuropsychiatric …

Mesolimbic dopamine signaling plays a major role in alcohol and substance use disorders
as well as comorbidities such as anxiety and depression. Growing evidence suggests that …

Dopamine (DA) is critically involved in different functions of the central nervous system
(CNS) including control of voluntary movement, affect, reward, sleep, and cognition. One of …

Monoamine dysfunctions in the prefrontal cortex (PFC) can contribute to diverse
neuropsychiatric disorders, including ADHD, bipolar disorder, PTSD and depression …

Cocaine is a powerful psychostimulant that is one of the most widely used illicit addictive.
The dopamine transporter (DAT) plays a major role in mediating cocaine's reward effect …

Dopaminergic neurotransmission has emerged as a critical determinant of stress
susceptibility and resilience. Although the dopamine transporter (DAT) is known to play a …

Chronic stress is a key factor in psychiatric and neurological disorders often worsening
disease symptoms. In this study, a unique animal model, the dopamine transporter knockout …

Since the identification of dopamine as a neurotransmitter in the mid-20th century,
investigators have examined the regulation of dopamine homeostasis at a basic biological …