Decoding physiological and pathological roles of innate immune cells in eye diseases: the perspectives from single-cell RNA sequencing
C Lu, X Mao, S Yuan - Frontiers in Immunology, 2024 - frontiersin.org
Single-cell RNA sequencing (scRNA-seq) has facilitated a deeper comprehension of the
molecular mechanisms behind eye diseases and has prompted the selection of precise …
molecular mechanisms behind eye diseases and has prompted the selection of precise …
[HTML][HTML] Mechanism and therapeutic targets of circulating immune cells in diabetic retinopathy
B Zhao, Y Zhao, X Sun - Pharmacological Research, 2024 - Elsevier
Diabetic retinopathy (DR) continues to be the leading cause of preventable vision loss
among working-aged adults, marked by immune dysregulation within the retinal …
among working-aged adults, marked by immune dysregulation within the retinal …
Mobilization of the innate immune response by a specific immunostimulant β-glucan confers resistance to chronic stress-induced depression-like behavior by …
J Ren, Y Zhang, H Pan, R Shi, H Zhu, R Yang… - International …, 2024 - Elsevier
Pre-stimulation of the innate immune response is an effective strategy to prevent depression-
like phenotypes in animals. However, the use of conventional immunostimulants may cause …
like phenotypes in animals. However, the use of conventional immunostimulants may cause …
Infectious Keratitis in Patients Over 65: A Review on Treatment and Preserving Eyesight
CK Kim, MZ Karslioglu, SH Zhao… - Clinical Interventions in …, 2024 - Taylor & Francis
Infectious keratitis (IK) represents a significant global health concern, ranking as the fifth
leading cause of blindness worldwide despite being largely preventable and treatable …
leading cause of blindness worldwide despite being largely preventable and treatable …
Oral administration of S-nitroso-l-glutathione (GSNO) provides anti-inflammatory and cytoprotective effects during ocular bacterial infections
Bacterial endophthalmitis is a severe complication of eye surgeries that can lead to vision
loss. Current treatment involves intravitreal antibiotic injections that control bacterial growth …
loss. Current treatment involves intravitreal antibiotic injections that control bacterial growth …
[HTML][HTML] Age-Associated Alterations in the Metabolome of Human Vitreous in Bacterial Endophthalmitis
S Maiti, L Gowtham, D Rudraprasad… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: Endophthalmitis is a severe inflammatory condition due to intraocular infections
that often leads to irreversible blindness. This study aimed to understand the age-dependent …
that often leads to irreversible blindness. This study aimed to understand the age-dependent …
Roles of biomaterials in modulating the innate immune response in ocular therapy
The eye is a hard-to-treat organ due to its poor regenerative capacity and susceptibility to
inflammation; as a result, it has an immune privilege mechanism. In the case of ocular …
inflammation; as a result, it has an immune privilege mechanism. In the case of ocular …