The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the
turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as …

Given the stochastic complexity of cancer diseases, the development of chemotherapeutic
drugs is almost limited by problems of selectivity and side effects. Furthermore, an …

Glioblastoma is a fatal brain tumor, and the standard treatment for this cancer is the surgical
removal of the tumor followed by chemotherapy with temozolomide and radiotherapy …

Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …

Cardiac remodeling is a common consequence of cardiovascular diseases and is closely
associated with oxidative stress, inflammation, and apoptosis. Germacrone, a bioactive …

One-carbon metabolism (OCM) is a series of connected pathways involving the methionine-
folate cycles, transsulfuration, polyamine synthesis, nucleotide synthesis, free-radical …

The rise in cancer cases in recent years is an alarming situation worldwide. Despite the
tremendous research and invention of new cancer therapies, the clinical outcomes are not …

DNA methylation is one of the earliest and most significant epigenetic mechanisms
discovered. DNA methylation refers, in general, to the addition of a methyl group to a specific …

Colorectal cancer (CRC) is the third most common cause of cancer death in men and
women. Chemotherapeutic drugs such as 5-fluorouracil (5-FU), irinotecan, and oxaliplatin …

Targeting the stemness of triple-negative breast cancer (TNBC) is a potential therapeutic
approach for treating TNBC. Tetrandrine, a natural plant alkaloid, has several anticancer …