Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that
affect the nervous system and heart, all of which are vital to the human body. To maintain …

A wide variety of acute and chronic neurodegenerative diseases, including
ischemic/traumatic brain injury, Alzheimer's disease, and Parkinson′ s disease, share …

Typically, Parkinson's disease (PD) is the second most prevalent neurodegenerative
disease in ageing individuals. It is now clear that genetic susceptibility and environmental …

In this review, we analyze the current hypotheses regarding energy metabolism in the
neurons and astroglia. Recently, it was shown that up to 20% of the total brain's energy is …

Parkinson's disease (PD) is characterized by the selective loss of dopaminergic nigrostriatal
neurons, which leads to disabling motor disturbances. Sulforaphane (SFN), found in …

Abstract In Persian Medicine (PM), PD (brain‐based tremor) is a known CNS disorder with
several therapeutic and preventive options. In their medical textbooks and pharmacopeias …

Generation of excessive reactive oxygen species (ROS) and advanced glycation end
products (AGEs), and cellular apoptosis are implicated in the pathogenesis of diabetic …

Hydrogen sulphide (H 2 S) is an endogenous gasotransmitter, largely known as a
pleiotropic mediator endowed with antioxidant, anti-inflammatory, pro-autophagic, and …

Chronic exposure to aluminium (Al) can contribute to the progression of several neurological
and neurodegenerative diseases. Al is a metal that promotes oxidative damage leading to …

Several studies suggest that an increase of glutathione (GSH) through activation of the
transcriptional nuclear factor (erythroid-derived 2)-like 2 (Nrf2) in the dopaminergic neurons …