Targeting the renin–angiotensin–aldosterone system to prevent hypertension and kidney disease of developmental origins

CN Hsu, YL Tain - International Journal of Molecular Sciences, 2021 - mdpi.com
The renin-angiotensin-aldosterone system (RAAS) is implicated in hypertension and kidney
disease. The developing kidney can be programmed by various early-life insults by so …

The good, the bad, and the ugly of pregnancy nutrients and developmental programming of adult disease

CN Hsu, YL Tain - Nutrients, 2019 - mdpi.com
Maternal nutrition plays a decisive role in developmental programming of many non-
communicable diseases (NCDs). A variety of nutritional insults during gestation can cause …

Epigenetics in the uterine environment: how maternal diet and ART may influence the epigenome in the offspring with long-term health consequences

I Peral-Sanchez, B Hojeij, DA Ojeda… - Genes, 2021 - mdpi.com
The societal burden of non-communicable disease is closely linked with environmental
exposures and lifestyle behaviours, including the adherence to a poor maternal diet from the …

Early life nutrition and mental health: the role of DNA methylation

RA Bekdash - Nutrients, 2021 - mdpi.com
Does the quality of our diet during early life impact our long-term mental health?
Accumulating evidence suggests that nutrition interacts with our genes and that there is a …

[HTML][HTML] The importance of maternal folate status for brain development and function of offspring

EFG Naninck, PC Stijger, EM Brouwer-Brolsma - Advances in Nutrition, 2019 - Elsevier
The importance of an adequate periconceptional maternal folate status to prevent fetal
neural tube defects has been well demonstrated and resulted in the recommendation for …

Developmental origins of chronic kidney disease: should we focus on early life?

YL Tain, CN Hsu - International journal of molecular sciences, 2017 - mdpi.com
Chronic kidney disease (CKD) is becoming a global burden, despite recent advances in
management. CKD can begin in early life by so-called “developmental programming” or …

Nutrition, the brain and cognitive decline: insights from epigenetics

MJ Dauncey - European journal of clinical nutrition, 2014 - nature.com
Nutrition affects the brain throughout life, with profound implications for cognitive decline and
dementia. These effects are mediated by changes in expression of multiple genes, and …

Biological pathways associated with vitamins in autism spectrum disorder

D Gusso, GRK Prauchner, AS Rieder, ATS Wyse - Neurotoxicity Research, 2023 - Springer
Autism spectrum disorder (ASD) is characterized by early-appearing social communication
deficits, with genetic and environmental factors potentially playing a role in its etiology …

Novel insights into the effect of vitamin B12 and omega-3 fatty acids on brain function

R Rathod, A Kale, S Joshi - Journal of Biomedical Science, 2016 - Springer
The prevalence of psychiatric disorders which are characterized by cognitive decline is
increasing at an alarming rate and account for a significant proportion of the global disease …

Effects of early-life malnutrition on neurodevelopment and neuropsychiatric disorders and the potential mechanisms

X Yan, X Zhao, J Li, L He, M Xu - Progress in Neuro-Psychopharmacology …, 2018 - Elsevier
Lines of evidence have demonstrated that early-life malnutrition is highly correlated with
neurodevelopment and adulthood neuropsychiatric disorders, while some findings are …