Despite the increasing prevalence of metabolic disorders, the potential effects of metabolic
factors on hepatocellular carcinoma (HCC) development in individuals with chronic liver …

Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers and is
characterized by high recurrence and heterogeneity, yet its mechanism is not well …

Liver cancer has a high incidence and mortality rate worldwide, with hepatocellular
carcinoma (HCC) being the most common histological type. With the decrease in the …

Background Studies of obesity with or without metabolic aberrations, commonly termed
metabolically unhealthy or healthy obesity, in relation to cancer risk are scarce. Methods We …

In pre‐disposed individuals, a reprogramming of the hepatic lipid metabolism may support
liver cancer initiation. We conducted a high‐resolution mass spectrometry based untargeted …

Abstract Background & Aims Little is known on the gender-specific effect and potential role
of non-linear associations between metabolic syndrome (MetS) components and liver …

Aim To investigate the causal relationship of serum lipid indicators and lipid-lowering drugs
with the risk of liver cancer using Mendelian randomization study. Methods A two-sample …

To explore the largely unknown etiology of small intestine cancer, we examined metabolic
factors and risk of small intestine cancer overall and by subtypes. Among 404 220 women …

Background: The inverse observational association between body mass index (BMI) and
lung cancer risk remains unclear. We assessed whether the association is explained by …

Aim Hepatobiliary and pancreatic (HBP) cancers are among the deadliest malignancies.
The objective of the study is to build cost‐effective models to identify high‐risk individuals for …