Cystic fibrosis: A worldwide analysis of CFTR mutations—correlation with incidence data and application to screening

JL Bobadilla, M Macek Jr, JP Fine… - Human mutation, 2002 - Wiley Online Library
Although there have been numerous reports from around the world of mutations in the gene
of chromosome 7 known as CFTR (cystic fibrosis transmembrane conductance regulator) …

Epidemiology and Genetics of cystic fibrosis in a SIA: in preparation for the Next‐Generation treatments

M Singh, C Rebordosa, J Bernholz, N Sharma - Respirology, 2015 - Wiley Online Library
Cystic fibrosis (CF) in the A sian population is less frequently reported due to under‐
diagnosis and lack of centralized CF patient registries. Clinical studies on CF cases from A …

Map of autosomal recessive genetic disorders in Saudi Arabia: concepts and future directions

M Al‐Owain, H Al‐Zaidan… - American Journal of …, 2012 - Wiley Online Library
Saudi Arabia has a population of 27.1 million. Prevalence of many autosomal recessive
disorders is higher than in other known populations. This is attributable to the high rate of …

Spectrum of mutations of cystic fibrosis in the 22 Arab countries: A systematic review

D Al‐Sadeq, T Abunada, R Dalloul, S Fahad… - …, 2019 - Wiley Online Library
Cystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the
CFTR gene, with various clinical manifestations that affect pulmonary, digestive, exocrine …

[HTML][HTML] The road for survival improvement of cystic fibrosis patients in Arab countries

H Banjar, G Angyalosi - International Journal of Pediatrics and Adolescent …, 2015 - Elsevier
Cystic fibrosis (CF) is a lethal, monogenic disorder that affects multiple organ systems of the
body. The incidence has been described before in the Middle East to be 1 in 2000 to 1 in …

Cystic fibrosis in India

SK Kabra, M Kabra, R Lodha… - Pediatric pulmonology, 2007 - Wiley Online Library
Cystic fibrosis (CF) was considered to be non‐existent in Indian subcontinent. Reports in last
one decade have suggested that cystic fibrosis occurs in India but its precise magnitude is …

The Saudi Thoracic Society guidelines for diagnosis and management of noncystic fibrosis bronchiectasis

H Al-Jahdali, A Alshimemeri, A Mobeireek… - Annals of Thoracic …, 2017 - journals.lww.com
This is the first guideline developed by the Saudi Thoracic Society for the diagnosis and
management of noncystic fibrosis bronchiectasis. Local experts including pulmonologists …

Genotype patterns for mutations of the cystic fibrosis transmembrane conductance regulator gene: a retrospective descriptive study from Saudi Arabia

HH Banjar, L Tuleimat, AAA El Seoudi… - Annals of Saudi …, 2020 - annsaudimed.net
ABSTRACT BACKGROUND: Cystic fibrosis (CF) occurs in populations in Saudi Arabia and
the Gulf area. Approximately 2000 known variants have been identified for the CF …

[HTML][HTML] Mutational spectrum of cystic fibrosis in the Lebanese population

C Farra, R Menassa, J Awwad, Y Morel… - Journal of cystic …, 2010 - Elsevier
BACKGROUND: Cystic fibrosis (CF) is the most common autosomal recessive disease in
Caucasians; it is however, considered to be rare in the Arab populations. Reports of the …

Dried blood spot-based metabolomic profiling in adults with cystic fibrosis

W Al-Qahtani, M Abdel Jabar, A Masood… - Journal of proteome …, 2020 - ACS Publications
Mucoviscidosis of the respiratory, gastrointestinal, and genitourinary tracts is the major
pathology in patients with cystic fibrosis (CF), a lethal monogenic panethnic and …