Gene co-expression networks (GCNs) have been developed as relevant analytical tools for the study of the gene expression patterns behind complex phenotypes. Determining the …
Clear cell renal carcinoma (ccRC) is a highly heterogeneous and progressively malignant disease. Analyzing ccRC progression in terms of modifications at the molecular and genetic …
Luminal A is the most common breast cancer molecular subtype in women worldwide. These tumors have characteristic yet heterogeneous alterations at the genomic and …
Gene co-expression networks have become a usual approach to integrate the vast amounts of information coming from gene expression studies in cancer cohorts. The reprogramming …
The study of co-expression programs in the context of cancer can help to elucidate the genetic mechanisms that are altered and lead to the disease. The identification of gene co …
Breast carcinomas are characterized by anomalous gene regulatory programs. As is well- known, gene expression programs are able to shape phenotypes. Hence, the understanding …
Transcriptional co-expression networks represent the concerted gene regulation programs by means of statistical inference of co-expression patterns. The rich phenomenology of …
Simple Summary Proteins are among the most fundamental building blocks and molecular players behind the functions of cells and tissues. Their abundance and interaction patterns …
Breast cancer is a complex, heterogeneous disease at the phenotypic and molecular level. In particular, the transcriptional regulatory programs are known to be significantly affected …