Loss of long distance co-expression in lung cancer

SD Andonegui-Elguera, JM Zamora-Fuentes… - Frontiers in …, 2021 - frontiersin.org
Lung cancer is one of the deadliest, most aggressive cancers. Abrupt changes in gene
expression represent an important challenge to understand and fight the disease. Gene co …

k-core genes underpin structural features of breast cancer

R Dorantes-Gilardi, D García-Cortés… - Scientific Reports, 2021 - nature.com
Gene co-expression networks (GCNs) have been developed as relevant analytical tools for
the study of the gene expression patterns behind complex phenotypes. Determining the …

Gene expression and co-expression networks are strongly altered through stages in clear cell renal carcinoma

JM Zamora-Fuentes, E Hernández-Lemus… - Frontiers in …, 2020 - frontiersin.org
Clear cell renal carcinoma (ccRC) is a highly heterogeneous and progressively malignant
disease. Analyzing ccRC progression in terms of modifications at the molecular and genetic …

Luminal a breast cancer co-expression network: Structural and functional alterations

D García-Cortés, E Hernández-Lemus… - Frontiers in …, 2021 - frontiersin.org
Luminal A is the most common breast cancer molecular subtype in women worldwide.
These tumors have characteristic yet heterogeneous alterations at the genomic and …

The role of copy number variants in gene co-expression patterns for luminal b breast tumors

C Hernández-Gómez, E Hernández-Lemus… - Frontiers in …, 2022 - frontiersin.org
Gene co-expression networks have become a usual approach to integrate the vast amounts
of information coming from gene expression studies in cancer cohorts. The reprogramming …

Multilayer approach reveals organizational principles disrupted in breast cancer co-expression networks

R Dorantes-Gilardi, D García-Cortés… - Applied Network …, 2020 - Springer
The study of co-expression programs in the context of cancer can help to elucidate the
genetic mechanisms that are altered and lead to the disease. The identification of gene co …

Gene co-expression is distance-dependent in breast cancer

D García-Cortés, G de Anda-Jáuregui, C Fresno… - Frontiers in …, 2020 - frontiersin.org
Breast carcinomas are characterized by anomalous gene regulatory programs. As is well-
known, gene expression programs are able to shape phenotypes. Hence, the understanding …

Functional and transcriptional connectivity of communities in breast cancer co-expression networks

G de Anda-Jáuregui, SA Alcalá-Corona… - Applied Network …, 2019 - Springer
Transcriptional co-expression networks represent the concerted gene regulation programs
by means of statistical inference of co-expression patterns. The rich phenomenology of …

The breast cancer protein co-expression landscape

M Ruhle, J Espinal-Enríquez, E Hernández-Lemus - Cancers, 2022 - mdpi.com
Simple Summary Proteins are among the most fundamental building blocks and molecular
players behind the functions of cells and tissues. Their abundance and interaction patterns …

Highly connected, non-redundant microRNA functional control in breast cancer molecular subtypes

G de Anda-Jáuregui, J Espinal-Enríquez… - Interface …, 2021 - royalsocietypublishing.org
Breast cancer is a complex, heterogeneous disease at the phenotypic and molecular level.
In particular, the transcriptional regulatory programs are known to be significantly affected …