HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …
Head and neck cancer
Head and neck cancer is the seventh most common type of cancer worldwide and comprise
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …
Reduced-dose radiation therapy for HPV-associated oropharyngeal carcinoma (NRG Oncology HN002)
SS Yom, P Torres-Saavedra, JJ Caudell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Reducing radiation treatment dose could improve the quality of life (QOL) of
patients with good-risk human papillomavirus–associated oropharyngeal squamous cell …
patients with good-risk human papillomavirus–associated oropharyngeal squamous cell …
Consensuses, controversies, and future directions in treatment deintensification for human papillomavirus‐associated oropharyngeal cancer
The most common cancer caused by human papillomavirus (HPV) infection in the United
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …
Hypoxia-directed treatment of human papillomavirus–related oropharyngeal carcinoma
NY Lee, EJ Sherman, HK Schöder, R Wray… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Standard curative-intent chemoradiotherapy for human papillomavirus (HPV)–
related oropharyngeal carcinoma results in significant toxicity. Since hypoxic tumors are …
related oropharyngeal carcinoma results in significant toxicity. Since hypoxic tumors are …
Detectable postoperative circulating tumor human papillomavirus DNA and association with recurrence in patients with HPV-associated oropharyngeal squamous cell …
DM Routman, S Kumar, BS Chera, KR Jethwa… - International Journal of …, 2022 - Elsevier
Purpose The purpose of our study is to determine the rate of detectability of ctHPVDNA after
surgery but before adjuvant therapy in patients with human papillomavirus (HPV)-associated …
surgery but before adjuvant therapy in patients with human papillomavirus (HPV)-associated …
Comparison of survival after transoral robotic surgery vs nonrobotic surgery in patients with early-stage oropharyngeal squamous cell carcinoma
Importance Transoral robotic surgery has been widely adopted since approval by the US
Food and Drug Administration in December 2009, despite limited comparative data …
Food and Drug Administration in December 2009, despite limited comparative data …
Deintensification of treatment for human papillomavirus-related oropharyngeal cancer: Current state and future directions
EO Bigelow, TY Seiwert, C Fakhry - Oral oncology, 2020 - Elsevier
Human papillomavirus (HPV)-related oropharyngeal squamous cell cancer (OPSCC) has
emerged as a distinct clinical entity of head and neck cancer with expected high survival …
emerged as a distinct clinical entity of head and neck cancer with expected high survival …
De-escalation strategies of (chemo) radiation for head-and-neck squamous cell cancers—HPV and beyond
A Rühle, AL Grosu, NH Nicolay - Cancers, 2021 - mdpi.com
Simple Summary HPV-related oropharyngeal squamous cell carcinoma patients have a very
good prognosis but are often suffering from long-term treatment-induced toxicities …
good prognosis but are often suffering from long-term treatment-induced toxicities …
The impact of head and neck radiotherapy on salivary flow and quality of life: Results of the ORARAD study
Objectives Salivary hypofunction and xerostomia, are common side effects of radiotherapy,
negatively impacting quality of life. The OraRad study presents results on the longitudinal …
negatively impacting quality of life. The OraRad study presents results on the longitudinal …