This review examines the large body of toxicological and epidemiological information on
human exposures to chlorpyrifos, with an emphasis on the controversial potential for …

Xenobiotics have been defined as chemicals to which an organism is exposed that are
extrinsic to the normal metabolism of that organism. Without metabolism, many xenobiotics …

Background A number of computational tools for metabolism prediction have been
developed over the last 20 years to predict the structures of small molecules undergoing …

Background Agricultural pesticide poisoning is a major public health problem in the
developing world, killing at least 250,000–370,000 people each year. Targeted pesticide …

Chlorpyrifos (CPF) is an organophosphorus pesticide widely used in agricultural
applications and household environments. 6-Gingerol-rich fraction from Zingiber officinale …

Sucralose is a synthetic organochlorine sweetener (OC) that is a common ingredient in the
world's food supply. Sucralose interacts with chemosensors in the alimentary tract that play a …

This is an overview of the metabolic activation of drugs, natural products, physiological
compounds, and general chemicals by the catalytic activity of cytochrome P450 enzymes …

Because pesticides may operate through different mechanisms, the authors studied the risk
of prostate cancer associated with specific pesticides in the Agricultural Health Study (1993 …

Organophosphorous pesticides are widely used in agriculture to control major insect pests.
Chlorpyrifos is one of the major organophosphorous pesticides which is used to control …

Traditional toxicology testing has relied on low-throughput, expensive mammalian studies;
however, timely testing of the large number of environmental toxicants requires new in vitro …