Non-motor features of Parkinson disease

AHV Schapira, KR Chaudhuri, P Jenner - Nature Reviews …, 2017 - nature.com
Many of the motor symptoms of Parkinson disease (PD) can be preceded, sometimes for
several years, by non-motor symptoms that include hyposmia, sleep disorders, depression …

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

MF Bastide, WG Meissner, B Picconi, S Fasano… - Progress in …, 2015 - Elsevier
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …

The impact of non‐motor symptoms on health‐related quality of life of patients with Parkinson's disease

P Martinez‐Martin, C Rodriguez‐Blazquez… - Movement …, 2011 - Wiley Online Library
Background: Non‐motor symptoms are detrimental to health‐related quality of life (HRQoL)
of Parkinson's disease patients. In this study, the Non‐Motor Symptoms Scale (NMSS) was …

Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment

KR Chaudhuri, AHV Schapira - The Lancet Neurology, 2009 - thelancet.com
Several studies, including work from the Parkinson's disease (PD) non-motor group and
others, have established that the non-motor symptoms of PD are common, occur across all …

Parkinson's disease: the non-motor issues

KR Chaudhuri, P Odin, A Antonini… - Parkinsonism & related …, 2011 - Elsevier
Non-motor symptoms (NMS) of Parkinson's disease remain the most under-appreciated and
under-researched when taken as a whole. Data is emerging that it is the “totaL” burden of …

[HTML][HTML] Levodopa-carbidopa intestinal gel in advanced Parkinson's: final results of the GLORIA registry

A Antonini, W Poewe, KR Chaudhuri, R Jech… - Parkinsonism & related …, 2017 - Elsevier
Introduction This registry evaluated the 24-month safety and efficacy of levodopa-carbidopa
intestinal gel (LCIG) treatment in advanced Parkinson's disease (PD) patients under routine …

[PDF][PDF] A review on Parkinson's disease treatment

TK Lee, EL Yankee - Neuroimmunol. Neuroinflamm, 2021 - f.oaes.cc
Parkinson's disease (PD) is a neurodegenerative illness and has a common onset between
the ages of 55 and 65 years. There is progressive development of both motor and non-motor …

Rotigotine effects on early morning motor function and sleep in Parkinson's disease: a double‐blind, randomized, placebo‐controlled study (RECOVER)

C Trenkwalder, B Kies, M Rudzinska, J Fine… - Movement …, 2011 - Wiley Online Library
In a multinational, double‐blind, placebo‐controlled trial (NCT00474058), 287 subjects with
Parkinson's disease (PD) and unsatisfactory early‐morning motor symptom control were …

Levodopa‐carbidopa intestinal gel in advanced Parkinson's disease: final 12‐month, open‐label results

HH Fernandez, DG Standaert, RA Hauser… - Movement …, 2015 - Wiley Online Library
Motor complications in Parkinson's disease (PD) are associated with long‐term oral
levodopa treatment and linked to pulsatile dopaminergic stimulation. l‐dopa‐carbidopa …

Gender-related differences in the burden of non-motor symptoms in Parkinson's disease

P Martinez-Martin, C Falup Pecurariu, P Odin… - Journal of …, 2012 - Springer
Differences in the expression of non-motor symptoms (NMS) by Parkinson's disease (PD)
patients may have important implications for their management and prognosis. Gender is a …