Cerebral stroke, which is one of the most frequent causes of mortality and leading cause of
disability in developed countries, often leads to devastating and irreversible brain damage …

Introduction Ischemic stroke (IS) is a major contributor to the global disease burden, and
effective biomarkers for IS management in clinical practice are urgently needed …

Aim Brain microvascular endothelial cells (BMVECs), as the important structure of blood-
brain barrier (BBB), play a vital role in ischemic stroke. Pyroptosis of different cells in the …

Ischemic stroke (IS) is the most prevalent type of stroke. The early diagnosis and prognosis
of IS are crucial for successful therapy and early intervention. Metabolomics, a tool in …

Coptisine (Cop) exerts a neuroprotective effect on central nervous system disease,
particularly ischemic stroke. However, its protective mechanism is still unclear. This study …

Introduction Brain tissue damage caused by ischemic stroke can trigger changes in the
body's metabolic response, and understanding the changes in the metabolic response of the …

Methamphetamine (METH) is a commonly abused addictive psychostimulant, and METH‐
induced neurotoxic and behavioural deficits are in a sex‐specific manner. However, there is …

Folic acid has a protective effect against ischemic stroke. However, the protective
pharmacological mechanism remains unclear. The aim of this study is to explore the …

Bai-Mi-Decoction (BMD), which is composed of Eugenia caryophyllata, Myristica fragrans,
Moschus berezovskii, and Crocus sativu, is a characteristic TCM multi-herb formula for brain …

Considering that neurotransmitters (NTs) and amino acids (AAs) exert pivotal roles in
various neurological diseases, global detection of these endogenous metabolites is of great …