Space travel has advanced significantly over the last six decades with astronauts spending
up to 6 months at the International Space Station. Nonetheless, the living environment while …

In space, multiple unique environmental factors, particularly microgravity and space
radiation, pose constant threat to the DNA integrity of living organisms. Specifically, space …

Radiotherapy is a form of cancer treatment that utilizes the ability of ionizing radiation to
induce cell inactivation and cell death, generally via inflicting DNA double-strand breaks …

Loss of muscle proteins and the consequent weakness has important clinical consequences
in diseases such as cancer, diabetes, chronic heart failure, and in aging. In fact, excessive …

Purpose To compile a list of genes that have been reported to be affected by external
ionizing radiation (IR) and to assess their performance as candidate biomarkers for …

In the mid-1980s, space experiments began to examine if microgravity could alter the
biological effects of space radiation. In the late 1990s, repair of DNA strand breaks was …

MicroRNAs (miRNAs) offer a new approach for molecular classification and individual
therapy of human cancer due to their regulation of oncogenic pathways. In a previous report …

Both microgravity and radiation exposure in the spaceflight environment have been
identified as hazards to astronaut health and performance. Substantial study has been …

Exposure to ionizing radiation (IR) is inevitable to humans in real-life scenarios; the hazards
of IR primarily stem from its mutagenic, carcinogenic, and cell killing ability. For many …

Astronaut intestinal health may be impacted by microgravity, radiation, and diet. The aim of
this study was to characterize how high and low linear energy transfer (LET) radiation …