Intrinsic disorder in the human vitreous proteome

M Antonietti, DJT Gonzalez, MB Djulbegovic… - International Journal of …, 2024 - Elsevier
The vitreous is a vital component of the eye, occupying a substantial portion of its volume
and maintaining its structure. This study delves into the presence and significance of …

A Computational Approach to Characterize the Protein S-Mer Tyrosine Kinase (PROS1-MERTK) Protein-Protein Interaction Dynamics

MB Djulbegovic, DJT Gonzalez, L Laratelli… - Cell biochemistry and …, 2024 - Springer
Protein S (PROS1) has recently been identified as a ligand for the TAM receptor MERTK,
influencing immune response and cell survival. The PROS1–MERTK interaction plays a role …

[HTML][HTML] AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma

DJT Gonzalez, MB Djulbegovic, M Sharma… - Ophthalmology …, 2024 - Elsevier
Objective Uveal melanoma (UM) poses significant diagnostic and prognostic challenges
due to its variable genetic landscape. We explore the use of a novel deep-learning tool to …

Comparative Analysis of the Intrinsic Disorder Within the Layers of the Human Cornea

MB Djulbegovic, M Antonietti, DJT Gonzalez, R Mattes… - Cornea, 2025 - journals.lww.com
Purpose: The human cornea is essential for vision, providing structural integrity and
refractive power to the eye. Recent advancements have deepened our understanding of the …

Ovarian expression of MerTK and its ligand Pros1 in non-pregnant estrus and pregnant mice

E Kirimlioglu, A Cernomorcenco, E Katirci - Journal of Molecular Histology, 2025 - Springer
Abstract Aim The interaction of MerTK, which negatively regulates immune responses, with
its ligand Pros1 contributes to the resolution of apoptosis and inflammation, participating in …

A Reversible Spherical Geometric Conversion of Protein Backbone Structure Coordinate Matrix to Three Independent Vectors of ρ, θ and φ

W Li - 2024 - preprints.org
Due to the vast conformational space proteins can adopt, accurate and efficient prediction of
protein structure remains still a challenging task, coupled with the intricacies of interatomic …