Gadolinium deposition in the brain: summary of evidence and recommendations

V Gulani, F Calamante, FG Shellock, E Kanal… - The Lancet …, 2017 - thelancet.com
Emerging evidence has linked MRI signal changes in deep nuclei of the brain with repeated
administration of gadolinium-based contrast agents. Gadolinium deposits have been …

Gadolinium deposition in brain: current scientific evidence and future perspectives

BJ Guo, ZL Yang, LJ Zhang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
In the past 4 years, many publications described a concentration-dependent deposition of
gadolinium in the brain both in adults and children, seen as high signal intensities in the …

Macrocyclic and other non–group 1 gadolinium contrast agents deposit low levels of gadolinium in brain and bone tissue: preliminary results from 9 patients with …

N Murata, LF Gonzalez-Cuyar, K Murata… - Investigative …, 2016 - journals.lww.com
Objective The purpose of this study was to determine whether gadolinium (Gd) is deposited
in brain and bone tissues in patients receiving only non–Group 1 agents, either macrocyclic …

Gadolinium deposition in human brain tissues after contrast-enhanced MR imaging in adult patients without intracranial abnormalities

RJ McDonald, JS McDonald, DF Kallmes, ME Jentoft… - Radiology, 2017 - pubs.rsna.org
Purpose To determine whether gadolinium deposits in neural tissues of patients with
intracranial abnormalities following intravenous gadolinium-based contrast agent (GBCA) …

Gadolinium deposition and nephrogenic systemic fibrosis: a radiologist's primer

M Mathur, JR Jones, JC Weinreb - Radiographics, 2020 - pubs.rsna.org
Gadolinium-based contrast agents (GBCAs) have an excellent safety profile. However, over
the last 2 decades, two specific concerns have surfaced. GBCAs are associated with …

Gadolinium deposition in the brain: current updates

JW Choi, WJ Moon - Korean journal of radiology, 2019 - synapse.koreamed.org
Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …

Contrast-enhanced spectral mammography vs. mammography and MRI–clinical performance in a multi-reader evaluation

EM Fallenberg, FF Schmitzberger, H Amer… - European …, 2017 - Springer
Objectives To compare the diagnostic performance of contrast-enhanced spectral
mammography (CESM) to digital mammography (MG) and magnetic resonance imaging …

Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration

J Davies, P Siebenhandl-Wolff, F Tranquart… - Archives of …, 2022 - Springer
Gadolinium-based contrast agents (GBCAs) have transformed magnetic resonance imaging
(MRI) by facilitating the use of contrast-enhanced MRI to allow vital clinical diagnosis in a …

Comparison of gadolinium concentrations within multiple rat organs after intravenous administration of linear versus macrocyclic gadolinium chelates

RJ McDonald, JS McDonald, D Dai, D Schroeder… - Radiology, 2017 - pubs.rsna.org
Purpose To compare gadolinium tissue concentrations of multiple linear and macrocyclic
chelates in a rat model to better understand the scope and extent of tissue deposition …

Quantification and assessment of the chemical form of residual gadolinium in the brain after repeated administration of gadolinium-based contrast agents: comparative …

T Frenzel, C Apte, G Jost, L Schöckel… - Investigative …, 2017 - journals.lww.com
Objective Multiple clinical and preclinical studies have reported a signal intensity increase
and the presence of gadolinium (Gd) in the brain after repeated administration of Gd-based …