Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin

A Salminen, K Kaarniranta, A Kauppinen - Inflammation Research, 2022 - Springer
Background Excessive exposure of the skin to UV radiation (UVR) triggers a remodeling of
the immune system and leads to the photoaging state which is reminiscent of chronological …

Modulation of the immune system by UV radiation: more than just the effects of vitamin D?

PH Hart, S Gorman, JJ Finlay-Jones - Nature Reviews Immunology, 2011 - nature.com
Humans obtain most of their vitamin D through the exposure of skin to sunlight. The
immunoregulatory properties of vitamin D have been demonstrated in studies showing that …

The human health effects of ozone depletion and interactions with climate change

M Norval, RM Lucas, AP Cullen, FR De Gruijl… - Photochemical & …, 2011 - pubs.rsc.org
Depletion of the stratospheric ozone layer has led to increased solar UV-B radiation (280–
315 nm) at the surface of the Earth. This change is likely to have had an impact on human …

A deep dive into UV-based phototherapy: Mechanisms of action and emerging molecular targets in inflammation and cancer

PA Vieyra-Garcia, P Wolf - Pharmacology & therapeutics, 2021 - Elsevier
UV-based phototherapy (including psoralen plus UVA (PUVA), UVB and UVA1) has a long,
successful history in the management of numerous cutaneous disorders. Photoresponsive …

Exposure to non-extreme solar UV daylight: spectral characterization, effects on skin and photoprotection

C Marionnet, C Tricaud, F Bernerd - International journal of molecular …, 2014 - mdpi.com
The link between chronic sun exposure of human skin and harmful clinical consequences
such as photo-aging and skin cancers is now indisputable. These effects are mostly due to …

Exposure to ultraviolet radiation in the modulation of human diseases

PH Hart, M Norval, SN Byrne… - Annual Review of …, 2019 - annualreviews.org
This review focuses primarily on the beneficial effects for human health of exposure to
ultraviolet radiation (UVR). UVR stimulates anti-inflammatory and immunosuppressive …

[HTML][HTML] European Code against Cancer 4th Edition: Ultraviolet radiation and cancer

R Greinert, E de Vries, F Erdmann, C Espina… - Cancer …, 2015 - Elsevier
Ultraviolet radiation (UVR) is part of the electromagnetic spectrum emitted naturally from the
sun or from artificial sources such as tanning devices. Acute skin reactions induced by UVR …

UV radiation suppresses experimental autoimmune encephalomyelitis independent of vitamin D production

BR Becklund, KS Severson… - Proceedings of the …, 2010 - National Acad Sciences
Although the exact cause of multiple sclerosis (MS) is unknown, a number of genetic and
environmental factors are thought to influence MS susceptibility. One potential …

The role of UV radiation and vitamin D in the seasonality and outcomes of infectious disease

AK Coussens - Photochemical & Photobiological Sciences, 2017 - pubs.rsc.org
The seasonality of infectious disease outbreaks suggests that environmental conditions
have a significant effect on disease risk. One of the major environmental factors that can …

Medical history, lifestyle, family history, and occupational risk factors for diffuse large B-cell lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project

JR Cerhan, A Kricker, O Paltiel… - Journal of the …, 2014 - academic.oup.com
Background Although risk factors for diffuse large B-cell lymphoma (DLBCL) have been
suggested, their independent effects, modification by sex, and association with anatomical …