Biochemistry of peroxynitrite and protein tyrosine nitration

G Ferrer-Sueta, N Campolo, M Trujillo… - Chemical …, 2018 - ACS Publications
Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …

An up-date on Giardia and giardiasis

E Einarsson, S Ma'ayeh, SG Svärd - Current opinion in microbiology, 2016 - Elsevier
Highlights•Giardiasis is a multifactorial diarrheal disease.•Giardia infection can be protective
against other diarrheal diseases.•Giardia infection can induce IBS and chronic fatigue …

[HTML][HTML] Advances in understanding Giardia: determinants and mechanisms of chronic sequelae

LA Bartelt, RB Sartor - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Giardia lamblia is a flagellated protozoan that is the most common cause of intestinal
parasitic infection in children living in resource-limited settings. The pathogenicity of Giardia …

Drug resistance in Giardia duodenalis

BRE Ansell, MJ McConville, SY Ma'ayeh… - Biotechnology …, 2015 - Elsevier
Giardia duodenalis is a microaerophilic parasite of the human gastrointestinal tract and a
major contributor to diarrheal and post-infectious chronic gastrointestinal disease world …

Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics

S Krakovka, U Ribacke, Y Miyamoto… - Frontiers in …, 2022 - frontiersin.org
Metronidazole (MTZ) is a clinically important antimicrobial agent that is active against both
bacterial and protozoan organisms. MTZ has been used extensively for more than 60 years …

Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping

A Siebieszuk, M Sejbuk, AM Witkowska - International Journal of …, 2023 - mdpi.com
The recently observed circadian oscillations of the intestinal microbiota underscore the
profound nature of the human–microbiome relationship and its importance for health …

Ultrastructural Alterations of the Human Pathogen Giardia intestinalis after Drug Treatment

M Benchimol, AP Gadelha, W de Souza - Pathogens, 2023 - mdpi.com
This review presents the main cell characteristics altered after in vitro incubation of the
parasite with commercial drugs used to treat the disease caused by Giardia intestinalis. This …

Relevance of peroxiredoxins in pathogenic microorganisms

MA de Oliveira, CA Tairum, LES Netto… - Applied Microbiology …, 2021 - Springer
The oxidative and nitrosative responses generated by animals and plants are important
defenses against infection and establishment of pathogenic microorganisms such as …

Transcriptional profiling of Giardia intestinalis in response to oxidative stress

SY Ma'ayeh, L Knörr, SG Svärd - International journal for parasitology, 2015 - Elsevier
Giardia intestinalis is a microaerophilic parasite that infects the human upper small intestine,
an environment that is fairly aerobic with reactive oxygen species being produced to fight off …

Cytotoxic effects of ivermectin on Giardia lamblia: induction of apoptosis and cell cycle arrest

FN Barzola, J Laiolo, C Cotelo, MB Joray… - Frontiers in …, 2024 - frontiersin.org
Introduction Giardia lamblia is a flagellated protozoan parasite causing giardiasis, a
common intestinal infection characterized by diarrhea, abdominal cramps, and nausea …