Cellular and molecular mechanisms of aflatoxin B1-mediated neurotoxicity: the therapeutic role of natural bioactive compounds

IA Adedara, OE Atanda, CSA Monteiro… - Environmental …, 2023 - Elsevier
Abstract Aflatoxin B 1 (AFB 1), a dietary toxin from the mold Aspergillus species, is well
acknowledged to elicit extra-hepatic toxicity in both animals and humans. The neurotoxicity …

Risk assessment of aflatoxins in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
EFSA was asked to deliver a scientific opinion on the risks to public health related to the
presence of aflatoxins in food. The risk assessment was confined to aflatoxin B1 (AFB 1) …

Risk assessment of ochratoxin A in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA to update their 2006 opinion on ochratoxin
A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and …

Updates on the effect of mycotoxins on male reproductive efficiency in mammals

D El. Khoury, S Fayjaloun, M Nassar, J Sahakian… - Toxins, 2019 - mdpi.com
Mycotoxins are ubiquitous and unavoidable harmful fungal products with the ability to cause
disease in both animals and humans, and are found in almost all types of foods, with a …

Aflatoxin B1 promotes autophagy associated with oxidative stress-related PI3K/AKT/mTOR signaling pathway in mice testis

W Huang, Z Cao, J Zhang, Q Ji, Y Li - Environmental Pollution, 2019 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is a hazard environmental pollutants and the most toxic one of
all the aflatoxins. AFB 1 can cause a serious impairment to testicular development and …

[HTML][HTML] Aflatoxin B1 causes oxidative stress and apoptosis in sheep testes associated with disrupting rumen microbiota

L Lin, Q Cao, C Zhang, T Xu, K Yue, Q Li, F Liu… - Ecotoxicology and …, 2022 - Elsevier
Abstract Aflatoxin B1 (AFB1) is an unavoidable environmental pollutant commonly found in
feed and foodstuffs. It is the most toxic one of all the aflatoxins, which can cause severe …

[HTML][HTML] Selenium deficiency aggravates aflatoxin B1–induced immunotoxicity in chick spleen by regulating 6 selenoprotein genes and redox/inflammation/apoptotic …

L Zhao, Y Feng, J Deng, NY Zhang, WP Zhang… - The Journal of …, 2019 - Elsevier
ABSTRACT Background Selenium (Se) plays a protective role in aflatoxin B 1 (AFB 1)–
induced splenic immunotoxicity in chicks. Objective This study was designed to reveal the …

Food mycotoxins: Dietary interventions implicated in the prevention of mycotoxicosis

V Sharma, V Patial - ACS Food Science & Technology, 2021 - ACS Publications
Mycotoxins are naturally occurring secondary metabolites produced by molds. These pose a
severe health risk to humans and livestock, leading to substantial economic losses …

Aflatoxin B1 impairs leydig cells through inhibiting AMPK/mTOR-mediated autophagy flux pathway

X Chen, C Li, Y Chen, C Ni, X Chen, L Zhang, X Xu… - Chemosphere, 2019 - Elsevier
Abstract Aflatoxin B1 (AFB1), a potential endocrine disrupter, has been shown to induce
hepatotoxicity in animal models, but the effects of AFB1 on Leydig cell function are unclear …

Gallic acid enhances reproductive function by modulating oxido-inflammatory and apoptosis mediators in rats exposed to aflatoxin-B1

SE Owumi, IA Adedara, AP Akomolafe… - Experimental …, 2020 - journals.sagepub.com
Aflatoxin B1 (AFB1) is reported to elicit adverse reproductive outcomes in animals. Gallic
acid (GA) is known to exhibit antioxidant and inflammatory bioactivities. The impact of GA on …