Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

SIRT1 is a highly conserved nicotinamide adenine dinucleotide (NAD+)-dependent histone
deacetylase. It is involved in the regulation of various pathophysiological processes …

Background The inflammatory response occurring in acute myocardial infarction (AMI) has
been proposed as a potential pharmacological target. Sodium-glucose co-transporter 2 …

Acute myocardial infarction remains the leading cause of death in humans. Timely
restoration of blood perfusion to ischemic myocardium remains the most effective strategy in …

Myocardial ischemia-reperfusion injury (IRI) is becoming a typical cardiovascular disease
with increasing worldwide incidence. It is usually induced by the restoration of normal blood …

The management of myocardial ischemia/reperfusion (I/R) damage in the context of
reperfusion treatment remains a significant hurdle in the field of cardiovascular disorders …

Myocardial ischemia-reperfusion injury (MIRI) results in the aggravation of myocardial injury
caused by rapid recanalization of the ischemic myocardium. In the past few years, there is a …

Increasing evidences demonstrate that chlorogenic acid (CGA), a polyphenol with multiple
effects such as anti-inflammatory and anti-oxidation, protects against myocardial ischemia …

The ketogenic diet (KD) has been used as a treatment for epilepsy since the 1920s, and its
role in the prevention of many other diseases is now being considered. In recent years, there …

Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …