Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugs

X Li, T Guo, Q Feng, T Bai, L Wu, Y Liu, X Zheng… - European Journal of …, 2022 - Elsevier
Many populations suffer from thrombotic disorders such as stroke, myocardial infarction,
unstable angina and thromboembolic disease. Thrombus is one of the major threatening …

Drug-delivery silver nanoparticles: A new perspective for phenindione as an anticoagulant

S Nikolova, M Milusheva, V Gledacheva… - Biomedicines, 2023 - mdpi.com
Anticoagulants prevent the blood from developing the coagulation process, which is the
primary cause of death in thromboembolic illnesses. Phenindione (PID) is a well-known …

Recent advancements in the synthesis and chemistry of benzo-fused nitrogen-and oxygen-based bioactive heterocycles

R Sharma, RK Yadav, R Sharma… - Current Topics in …, 2021 - ingentaconnect.com
Since a variety of benzo-fused nitrogen-and oxygen-based bioactive heterocyclic moieties
are present in the form of benzoxazinones, spirooxindole-based heterocyclic compounds …

Diamino-Terephthalonitrile-based Single Benzene Fluorophores Featuring Strong Solution State Fluorescence and Large Stokes Shifts

T Raghava, S Banerjee… - The Journal of Organic …, 2023 - ACS Publications
1°-and 2°-amines react with tetrafluoroterephthalonitrile through SNAr chemistry, creating
the strongly emissive para-diamino-terephthalonitrile type single benzene fluorophores. The …

On Water: Silver-Catalyzed Domino Approach for the Synthesis of Benzoxazine/Oxazine-Fused Isoquinolines and Naphthyridines from o-Alkynyl Aldehydes

AK Verma, D Choudhary, RK Saunthwal… - The Journal of …, 2013 - ACS Publications
An operationally simple domino approach for the silver-catalyzed synthesis of
oxazine/benzoxazine-fused isoquinolines 5a–q and naphthyridines 6a–v by the reaction of …

1, 4-Substituted triazoles as nonsteroidal anti-androgens for prostate cancer treatment

C Ferroni, A Pepe, YS Kim, S Lee… - Journal of medicinal …, 2017 - ACS Publications
Prostate cancer (PC) is the fifth leading cause of cancer death in men, and the androgen
receptor (AR) represents the primary target for PC treatment, even though the disease …

Diastereoselective Spirocyclization of Benzoxazines with Nitroalkenes via Rhodium-Catalyzed C–H Functionalization/Annulation Cascade under Mild Conditions

A Mishra, A Bhowmik, S Samanta, W Sarkar… - Organic …, 2020 - ACS Publications
A Rh (III)-catalyzed [3+ 2] annulation of benzoxazines with nitroolefins that proceeds via
redox-neutral C–H functionalization has been demonstrated, leading to the novel class of …

An enolate ion as a synthon in biocatalytic synthesis of 3, 4-dihydro-2 (1 H)-quinoxalinones and 3, 4-dihydro-1, 4-benzoxazin-2-ones: lemon juice as an alternative to …

J Petronijević, Z Bugarčić, GA Bogdanović… - Green …, 2017 - pubs.rsc.org
Innovative, efficient, clean, experimentally simple and environmentally friendly one-pot
biocatalytic synthesis of two small libraries of 3, 4-dihydro-2 (1H)-quinoxalinones (4a–m) …

Rh (iii)-catalyzed [3+ 2] spiroannulation of 2, 3-dihydro-1, 4-benzoxazines with 4-hydroxy-2-alkynoates through ortho-C–H bond functionalization

K Nagesh, J Manda, B Sridhar… - Organic & Biomolecular …, 2023 - pubs.rsc.org
Rhodium (III)-catalyzed [3+ 2]-spiroannulation of 2-aryl-1, 4-benzoxazines with 4-hydroxy-2-
alkynoates has been developed for the synthesis of highly rigid spirolactones in good yields …

Transition-metal-free synthesis of trifluoromethylated benzoxazines via a visible-light-promoted tandem difunctionalization of o-vinylanilides with …

P Natarajan, D Chuskit - New Journal of Chemistry, 2022 - pubs.rsc.org
9, 10-Phenanthrenedione (PQ) visible-light photocatalysis for the synthesis of a series of
trifluoromethylated benzoxazines in good to excellent yields has been developed by using N …