Cancer/testis antigens: expression, regulation, tumor invasion, and use in immunotherapy of cancers

A Salmaninejad, MR Zamani… - Immunological …, 2016 - Taylor & Francis
Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …

A role of the TEX101 interactome in the common aetiology behind male subfertility and testicular germ cell tumor

J Burton, MW Wojewodzic, TB Rounge… - Frontiers in …, 2022 - frontiersin.org
Patients who develop testicular germ cell tumours (TGCT) are at higher risk to be subfertile
than the general population. The conditions are believed to originate during foetal life …

Titanium dioxide nanoparticle-induced testicular damage, spermatogenesis suppression, and gene expression alterations in male mice

G Gao, Y Ze, X Zhao, X Sang, L Zheng, X Ze… - Journal of hazardous …, 2013 - Elsevier
Although titanium dioxide nanoparticles (TiO 2 NPs) have been demonstrated to accumulate
in organs resulting in toxicity, there is currently only limited data regarding male reproductive …

Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer

S Ghafouri-Fard, ZO Ashtiani, BS Golian… - Archives of medical …, 2010 - Elsevier
BACKGROUND AND AIMS: Screening methods for early detection of prostate cancer have
some limitations regarding specificity and sensitivity, so there is a continuing search to find …

[HTML][HTML] Bioinformatics analysis of the genes involved in the extension of prostate cancer to adjacent lymph nodes by supervised and unsupervised machine learning …

E Shamsara, J Shamsara - Genomics, 2020 - Elsevier
The present study aimed to identify the genes associated with the involvement of adjunct
lymph nodes of patients with prostate cancer (PCa) and to provide valuable information for …

[HTML][HTML] Expression of testis specific genes TSGA10, TEX101 and ODF3 in breast cancer

M Dianatpour, P Mehdipour, K Nayernia… - Iranian Red Crescent …, 2012 - ncbi.nlm.nih.gov
Background Breast cancer is the most common malignancy in women around the world so
finding new biomarkers for early detection and also study on molecular aspects of breast …

Peptide vaccine from cancer-testis antigen ODF2 can potentiate the cytotoxic T lymphocyte infiltration through IL-15 in non-MSI-H colorectal cancer

R Shi, X Zhou, L Pang, M Wang, Y Li, C Chen… - Cancer Immunology …, 2023 - Springer
About 85% of patients with colorectal cancer (CRC) have the non-microsatellite instability-
high (non-MSI-H) subtype, and many cannot benefit from immune checkpoint blockade. A …

Novel regulators of spermatogenesis

KL Fok, H Chen, YC Ruan, HC Chan - Seminars in Cell & Developmental …, 2014 - Elsevier
Spermatogenesis is a multistep process that supports the production of millions of sperm
daily. Understanding of the molecular mechanisms that regulate spermatogenesis has been …

Melanoma: a prototype of cancer-testis antigen-expressing malignancies

S Faramarzi, S Ghafouri-Fard - Immunotherapy, 2017 - Taylor & Francis
Melanoma is the first malignancy in which expression and immunogenicity of cancer-testis
antigens (CTAs) have been documented. Several CTAs have been shown to be expressed …

[HTML][HTML] Long non coding RNA expression intersecting cancer and spermatogenesis: a systematic review

A Dianatpour, S Ghafouri-Fard - Asian Pacific journal of cancer …, 2017 - ncbi.nlm.nih.gov
Background: Numerous similarities have been noted between gametogenic and tumorigenic
programs in features such as global hypomethylation, immune evasion, immortalization …