Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and
pain-related disability, which are expected to rise with the rapid global population aging …

Abstract Purpose of Review Management of acute pain following surgery using a multimodal
approach is recommended by the American Society of Anesthesiologists whenever …

Opioid use has risen dramatically in the past three decades. In the USA, opioid overdose
has become a leading cause of unintentional death, surpassing motor vehicle accidents. A …

Multimodal analgesia is defined as the use of more than one pharmacological class of
analgesic medication targeting different receptors along the pain pathway with the goal of …

Background: Various multimodal analgesic approaches have been proposed for spine
surgery. The authors evaluated the effect of using a combination of four nonopioid …

Adequate pain control after hip and knee arthroplasty is essential to maximize postoperative
rehabilitation, minimize complications, and ensure patient satisfaction. Opioid use …

Offering expert, comprehensive guidance on the basic science, diagnosis, and treatment of
acute musculoskeletal injuries and post-traumatic reconstructive problems, Skeletal Trauma …

The United States is facing the worst drug crisis in US history, with more than 63,600 drug
overdose deaths in 2016, almost double the deaths caused by traffic accidents or gun …

Orthopedic surgery was one of the first specialties to embrace multimodal analgesia and
incorporate it into practice more than a decade ago. Orthopedic surgeries are considered to …

Postoperative pain is a common but often inadequately treated condition. Enhanced
recovery pathways (ERPs) are increasingly being utilized to standardize perioperative care …