The immune system plays a pivotal role in the initiation, development and resolution of
inflammation following insult or damage to organs. The heart is a vital organ which supplies …

Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation
syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening …

It is generally regarded that the progression of an infection within host macrophages is the
consequence of a failed immune response. However, recent appreciation of macrophage …

Neutrophils are attracted to and generate dense swarms at sites of cell damage in diverse
tissues, often extending the local disruption of organ architecture produced by the initial …

The macrophage is a key cell in the pro-and anti-inflammatory response including that of the
inflammatory microenvironment of malignant tumors. Much current drug development in …

Tumor-associated macrophages are an abundant cell type in the tumor microenvironment.
These macrophages serve as a promising target for treatment of cancer due to their roles in …

The contribution of dendritic cell (DC) antigen cross-presentation to the activation of CD8+ T
lymphocytes for immune defense against tumors, viruses, and intracellular pathogens has …

Breast cancer is the most commonly diagnosed cancer in women worldwide, and> 90% of
breast cancer-related deaths are associated with metastasis. Breast cancer spreads …

Tissue-resident mast cells are associated with many inflammatory and physiological
processes. Although mast cells arise from the yolk sac, the exact ontogeny of adult mast …

Macrophages facilitate essential homeostatic functions eg, endocytosis, phagocytosis, and
signaling during inflammation, and express a variety of scavenger receptors including …